Evidence map›Paper›PMID 37308041›Full record

ArticlePharmacology, biochemistry, and behavior2023

Substance use disorder is the outcome of deviant socialization: A prospective investigation spanning childhood to adulthood.

Maureen Reynolds, Levent Kirisci, Zu Wei Zhai, Ralph Tarter

Open access · greenAbstract read
In one paragraph

Article in Pharmacology, biochemistry, and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Maureen ReynoldsDepartment of Pharmaceutical Sciences, University of Pittsburgh, School of Pharmacy, 3501 Terrace Street, 10064 Salk Hall, Pittsburgh, PA 15261, United States of America. Electronic address: maureen@pitt.edu.
Levent KirisciDepartment of Pharmaceutical Sciences, University of Pittsburgh, School of Pharmacy, 3501 Terrace Street, 10064 Salk Hall, Pittsburgh, PA 15261, United States of America.
Zu Wei ZhaiProgram in Neuroscience, Middlebury College, McCardell Bicentennial Hall, Middlebury, VT 05753, United States of America.
Ralph TarterDepartment of Pharmaceutical Sciences, University of Pittsburgh, School of Pharmacy, 3501 Terrace Street, 10064 Salk Hall, Pittsburgh, PA 15261, United States of America.
University of Pittsburgh · USMiddlebury College · US

Funding

TRANSLATION MODULEP50DA005605 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RIDENOUR, TY A · 1989 to 2014
$25.7M
NIDA NIH HHS P50 DA005605
6 · The paper itself

Abstract

objectiveDisinhibitory behavior during childhood and adolescence has been frequently shown to amplify the risk for substance use disorder (SUD) in adulthood. This prospective study examined the hypothesis that poor communication with parents and association with deviant peers comprise an SUD-promoting environtype which catalyzes transition of disinhibitory behavior toward SUD.

methodMale (N = 499) and female (N = 195) youths were tracked from 10 to 12 to 30 years of age. Path analysis evaluated the patterning of disinhibitory behavior and social environment during childhood on substance use during adolescence, and antisocial personality without co-occurring SUD in early adulthood and subsequently substance use disorder (SUD).

resultsDisinhibitory behavior (SUD vulnerability) in childhood predicts antisociality without SUD (age 22) that segues to SUD (age 23-30) whereas the environtype (parents and peers) predicts substance use during adolescence which predicts antisocial personality leading to SUD. Antisociality without SUD in early adulthood mediates the association of substance use during adolescence and SUD.

conclusionDisinhibitory behavior and deviance-promoting social environment conjointly promote development of SUD via deviant socialization.

Indexed as

SocializationSubstance-Related DisordersAdolescentAdultAntisocial Personality DisorderChildFemaleHumansMalePeer GroupProspective StudiesYoung AdultAdolescenceAntisocial personalityParental relationshipPeer relationshipsSubstance useSubstance use disorder etiology

Identifiers

PMID37308041
PMCPMC10357486
OpenAlexW4380204333

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.