ReviewPlant & cell physiology2023
Exploring the Evolvability of Plant Specialized Metabolism: Uniqueness Out Of Uniformity and Uniqueness Behind Uniformity.
Review in Plant & cell physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- A case study of evolutionary variability and determinism among type III polyketide synthases.Nature communications · 2026Article
- Polyphenol profiling and multi-target antioxidant, anti-inflammatory and antidiabetic activity of Sorbus commixta Hedl. leaves.Scientific reports · 2026Article
- Dynamic diversification of lignan metabolism in sesame via coordinated oxygenation and glucosylation across germination.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Transposon-colonized intron gain follows parasitism-mediated horizontal transfer of a cytochrome P450 gene.Plant physiology · 2026Article
- Volatile Organic Compounds ofPlants (Basel, Switzerland) · 2026Article
- Insights into glandular trichome biology from analysis of organ-specific gene expression programmes in cannabis, hop and tomato.The Plant journal : for cell and molecular biology · 2026Article
- Acteoside exerts neuroprotective effects by preventing α-synuclein aggregation and oxidative stress in models of Parkinson's disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Article
- Convergence and constraint in glucosinolate evolution across the Brassicaceae.The Plant cell · 2025Article
- Chemical trios in rhizosphere ecology: Emerging roles of microbial volatiles, root-derived volatiles, and non-volatile root exudates in plant-soil microbe interactions.Plant biotechnology (Tokyo, Japan) · 2025Article
- Fine-tuned terpene synthase gene expression, functional promiscuity, and subcellular localization: implications for the evolution of complex floral volatile bouquet in Caladenia orchids.Plant & cell physiology · 2025Article
- Omics-based identification of the broader effects of 2-hydroxyisoflavanone synthase gene editing on a gene regulatory network beyond isoflavonoid loss in soybean hairy roots.Plant & cell physiology · 2025Article
- Adaptive Changes and Genetic Mechanisms in Organisms Under Controlled Conditions: A Review.International journal of molecular sciences · 2025Review
- Refining our understanding of the diversity of plant specialised metabolites.The New phytologist · 2025Article
- The evolution of plant responses underlying specialized metabolism in host-pathogen interactions.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Biotic interactions, evolutionary forces and the pan-plant specialized metabolism.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Multi-omics signatures of diverse plant callus cultures.Plant biotechnology (Tokyo, Japan) · 2024Article
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2 authors.
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Abstract
The huge structural diversity exhibited by plant specialized metabolites has primarily been considered to result from the catalytic specificity of their biosynthetic enzymes. Accordingly, enzyme gene multiplication and functional differentiation through spontaneous mutations have been established as the molecular mechanisms that drive metabolic evolution. Nevertheless, how plants have assembled and maintained such metabolic enzyme genes and the typical clusters that are observed in plant genomes, as well as why identical specialized metabolites often exist in phylogenetically remote lineages, is currently only poorly explained by a concept known as convergent evolution. Here, we compile recent knowledge on the co-presence of metabolic modules that are common in the plant kingdom but have evolved under specific historical and contextual constraints defined by the physicochemical properties of each plant specialized metabolite and the genetic presets of the biosynthetic genes. Furthermore, we discuss a common manner to generate uncommon metabolites (uniqueness out of uniformity) and an uncommon manner to generate common metabolites (uniqueness behind uniformity). This review describes the emerging aspects of the evolvability of plant specialized metabolism that underlie the vast structural diversity of plant specialized metabolites in nature.
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