Evidence map›Paper›PMID 37307404›Full record

ArticleJournal of cellular and molecular medicine2023

Melatonin regulates cancer migration and stemness and enhances the anti-tumour effect of cisplatin.

Linglin Cheng, Shubo Li, Kailun He, Ye Kang, Tianye Li, Chunting Li, Yi Zhang, Wanlu Zhang, Yongye Huang

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

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  10. Melatonin for gastric cancer treatment: where do we stand?Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Linglin ChengCollege of Life and Health Sciences, Northeastern University, Shenyang, China.
Shubo LiLiaoning Center for Animal Disease Control and Prevention, Liaoning Agricultural Development Service Center, Shenyang, China.
Kailun HeCollege of Life and Health Sciences, Northeastern University, Shenyang, China.
Ye KangDepartment of Pathology, Shengjing Hospital of China Medical University, Shenyang, China.
Tianye LiCollege of Life and Health Sciences, Northeastern University, Shenyang, China.
Chunting LiCollege of Life and Health Sciences, Northeastern University, Shenyang, China.
Yi ZhangCollege of Life and Health Sciences, Northeastern University, Shenyang, China.
Wanlu ZhangCollege of Life and Health Sciences, Northeastern University, Shenyang, China.
Yongye HuangCollege of Life and Health Sciences, Northeastern University, Shenyang, China.ORCID 0000-0002-9083-250X
Northeastern University · CNChina Medical University · CNShenyang Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melatonin, a lipophilic hormone released from the pineal gland, has oncostatic effects on various types of cancers. However, its cancer treatment potential needs to be improved by deciphering its corresponding mechanisms of action and optimising therapeutic strategy. In the present study, melatonin inhibited gastric cancer cell migration and soft agar colony formation. Magnetic-activated cell sorting was applied to isolate CD133

Indexed as

MelatoninStomach NeoplasmsApoptosisCell Line, TumorCell ProliferationCisplatinHumansSignal TransductionCisplatinMelatonincancer stem cellscisplatincombinatorial treatmentgastric cancermelatonin

Identifiers

PMID37307404
PMCPMC10399526
OpenAlexW4380366528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.