SynthesisHip international : the journal of clinical and experimental research on hip pathology and therapy2024
Pain, function and quality of life are impaired in adults undergoing periacetabular osteotomy (PAO) for hip dysplasia: a systematic review and meta-analysis.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Substantial blood loss and transfusion burden after periacetabular osteotomy: Benchmark estimates from a systematic review and meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Pooled it
- Physical impairments in Adults with Developmental Dysplasia of the Hip (DDH) undergoing Periacetabular osteotomy (PAO): A Systematic Review and Meta-Analysis.International journal of sports physical therapy · 2022Pooled it
- Trends in periacetabular osteotomy for dysplastic hip in South Korea: a ten year analysis of national health insurance data.International orthopaedics · 2026Article
- Association of tranexamic acid use and autologous predonation with blood loss and transfusion outcomes after periacetabular osteotomy: An arm-based multilevel meta analysis.Journal of experimental orthopaedics · 2026Review
- Return to work after periacetabular osteotomy: workload as a determinant of occupational trajectories.Bone & joint open · 2026Article
- Periacetabular osteotomy provides durable correction and low arthroplasty conversion at ≥ 7 years: prospective middle eastern study.International orthopaedics · 2026Article
- Durable Mid-Term Outcomes and High Rates of Meaningful Improvement After Hip Arthroscopy With Concomitant Periacetabular Osteotomy.Arthroscopy, sports medicine, and rehabilitation · 2025Article
- Validation of the Aarhus periacetabular osteotomy database.Archives of orthopaedic and trauma surgery · 2025Article
- Anticipating Time Taken off Work After Bernese Periacetabular Osteotomy: A Single-Surgeon Experience of 282 Cases.Arthroplasty today · 2025Article
- Morphology of the dysplastic hip and the relationship with sex and acetabular version.Clinical anatomy (New York, N.Y.) · 2025Observational
- Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHip dysplasia is a common condition in active adults with hip pain that can lead to joint degeneration. Periacetabular osteotomy (PAO) is a common surgical treatment for hip dysplasia. The effect of this surgery on pain, function and quality of life (QOL) has not been systematically analysed. PURPOSE: In adults with hip dysplasia: (1) evaluate differences in pain, function and QOL in those undergoing PAO and healthy controls; (2) evaluate pre- to post-PAO changes in pain, function and QOL; (3) evaluate differences in pain, function and QOL in those with mild versus severe dysplasia, undergoing PAO; and (4) evaluate differences in pain, function and QOL in those having primary PAO versus those with previous hip arthroscopy.
methodsA comprehensive, reproducible search strategy was performed on 5 different databases. We included studies that assessed pain, function and QOL in adults undergoing PAO for hip dysplasia, using hip-specific patient reported outcomes measures.
resultsFrom 5017 titles and abstracts screened, 62 studies were included. Meta-analysis showed PAO patients had worse outcomes pre- and post-PAO compared to healthy participants. Specifically, pain (standardised mean difference [SMD] 95% confidence interval [CI]): -4.05; -4.78 to -3.32), function (-2.81; -3.89 to -1.74), and QOL (-4.10; -4.43 to -3.77) were significantly poorer preoperatively.Meta-analysis found patients experienced improvements following PAO. Pain improved from pre-surgery to 1-year (standardised paired difference [SPD] 1.35; 95% CI, 1.02-1.67) and 2 years postoperatively (1.35; 1.16-1.54). For function, the activities of daily living scores at 1 year (1.22; 1.09-1.35) and 2 years (1.06; 0.9-1.22) and QOL at 1 year (1.36; 1.22-1.5) and 2 years (1.3; 1.1-1.5) all improved. No difference was found between patients undergoing PAO with mild versus severe dysplasia.
conclusionsBefore undergoing PAO surgery, adults with hip dysplasia have worse levels of pain, function and QOL compared to healthy participants. These levels improve following PAO, but do not reach the same level as their healthy participants. REGISTRATION: PROSPERO (CRD42020144748).
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