Evidence map›Paper›PMID 37306011›Full record

ArticleProteins2023

New prediction categories in CASP15.

Andriy Kryshtafovych, Maciej Antczak, Marta Szachniuk, Tomasz Zok, Rachael C Kretsch, Ramya Rangan, Phillip Pham, Rhiju Das, Xavier Robin, Gabriel Studer and 7 more

Abstract read
In one paragraph

Article in Proteins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Evaluating generalization in protein-ligand cofolding methods.Nature structural & molecular biology · 2026
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  13. How AI can help us beat AMR.npj antimicrobials and resistance · 2025
    Review
  14. The Need for Continuing Blinded Pose- and Activity Prediction Benchmarks.Journal of chemical information and modeling · 2025
    Review
  15. Review
  16. Recent advances and challenges in protein complex model accuracy estimation.Computational and structural biotechnology journal · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Andriy KryshtafovychGenome Center, University of California, Davis, California, USA.ORCID 0000-0001-5066-7178
Maciej AntczakInstitute of Computing Science, Poznan University of Technology, Poznan, Poland.
Marta SzachniukInstitute of Computing Science, Poznan University of Technology, Poznan, Poland.ORCID 0000-0002-8724-7908
Tomasz ZokInstitute of Computing Science, Poznan University of Technology, Poznan, Poland.
Rachael C KretschBiophysics Program, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0002-6935-518X
Ramya RanganBiophysics Program, Stanford University School of Medicine, Stanford, California, USA.
Phillip PhamBiochemistry Department, Stanford University School of Medicine, Stanford, California, USA.
Rhiju DasBiochemistry Department, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0001-7497-0972
Xavier RobinBiozentrum, University of Basel, Basel, Switzerland.ORCID 0000-0002-6813-3200
Gabriel StuderBiozentrum, University of Basel, Basel, Switzerland.ORCID 0000-0003-0462-1456
Janani DurairajBiozentrum, University of Basel, Basel, Switzerland.
Jerome EberhardtBiozentrum, University of Basel, Basel, Switzerland.
Aaron SweeneyCentre for Structural Systems Biology (CSSB), Leibniz-Institut für Virologie (LIV), Hamburg, Germany.
Maya TopfCentre for Structural Systems Biology (CSSB), Leibniz-Institut für Virologie (LIV), Hamburg, Germany.
Torsten SchwedeBiozentrum, University of Basel, Basel, Switzerland.ORCID 0000-0003-2715-335X
Krzysztof FidelisGenome Center, University of California, Davis, California, USA.ORCID 0000-0002-8061-412X
John MoultInstitute for Bioscience and Biotechnology Research, Department of Cell Biology and Molecular genetics, University of Maryland, Rockville, Maryland, USA.

Funding

Prospective analysis to determine model accuracy performance and boundaries in the post-AlphaFold2 environmentR01GM100482 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FIDELIS, KRZYSZTOF A · 2012 to 2025
$11.1M
Next-generation computational/chemical methods for complex RNA structuresR35GM122579 · NIGMS · STANFORD UNIVERSITY · PI Rhiju Das · 2017 to 2026
$7.2M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM100482NIGMS NIH HHS R35 GM122579NIH HHS R35 GM122579Wellcome Trust 209250/Z/17/Z
6 · The paper itself

Abstract

Prediction categories in the Critical Assessment of Structure Prediction (CASP) experiments change with the need to address specific problems in structure modeling. In CASP15, four new prediction categories were introduced: RNA structure, ligand-protein complexes, accuracy of oligomeric structures and their interfaces, and ensembles of alternative conformations. This paper lists technical specifications for these categories and describes their integration in the CASP data management system.

Indexed as

Computational BiologyProteinsLigandsModels, MolecularProtein ConformationLigandsProteins3D structure predictionCASP15protein-ligand complexesprotein structureRNA structure

Identifiers

PMID37306011
PMCPMC10713864

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.