Evidence map›Paper›PMID 37305984›Full record

ArticleAlimentary pharmacology & therapeutics2023

Accuracy of ultrasound, bioelectrical impedance analysis and anthropometry as point-of-care measurements of skeletal muscle mass in patients with inflammatory bowel disease.

Anke L Nguyen, Megan Burns, Madhuni Herath, Kate Lambell, Darcy Holt, Jessica Fitzpatrick, Frances Milat, Peter R Ebeling, Peter R Gibson, Gregory T Moore

Abstract read
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Article in Alimentary pharmacology & therapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Anke L NguyenGastroenterology Department, Monash Health, Victoria, Melbourne, Australia.ORCID 0000-0003-1210-3325
Megan BurnsGastroenterology Department, Monash Health, Victoria, Melbourne, Australia.ORCID 0000-0003-2602-1638
Madhuni HerathEndocrinology Department, Monash Health, Victoria, Melbourne, Australia.ORCID 0000-0003-2776-2083
Kate LambellNutrition Department, Alfred Health, Victoria, Melbourne, Australia.ORCID 0000-0002-4816-3023
Darcy HoltGastroenterology Department, Monash Health, Victoria, Melbourne, Australia.ORCID 0000-0001-7752-6279
Jessica FitzpatrickDepartment of Gastroenterology, Central Clinical School, Monash University and Alfred Health, Victoria, Melbourne, Australia.ORCID 0000-0002-7811-8135
Frances MilatDepartment of Medicine, School of Clinical Sciences, Monash University, Victoria, Melbourne, Australia.ORCID 0000-0002-9940-4376
Peter R EbelingEndocrinology Department, Monash Health, Victoria, Melbourne, Australia.ORCID 0000-0002-2921-3742
Peter R GibsonDepartment of Gastroenterology, Central Clinical School, Monash University and Alfred Health, Victoria, Melbourne, Australia.ORCID 0000-0001-9108-1712
Gregory T MooreGastroenterology Department, Monash Health, Victoria, Melbourne, Australia.ORCID 0000-0002-3689-8858

Funding

Crohn's Colitis Australia PhD ScholarshipNational Health and Medical Research Council ScholarshipResearch Training Program Stipend (Monash University)
6 · The paper itself

Abstract

backgroundDisturbance of skeletal muscle mass has clinically important implications in patients with inflammatory bowel disease (IBD), but accurate quantification requires radiation-intense techniques.

aimsWe aimed to compare point-of-care muscle assessments and their change with therapy with those using reference-standard whole-body dual energy X-ray absorptiometry (DXA).

methodsAdult patients with IBD and healthy controls underwent prospective assessment of muscularity by ultrasound of the dominant arm and both thighs, bioelectrical impedance analysis (BIA), anthropometric measurements, and DXA. Patients with active IBD were assessed again ≥13 weeks after initiating biologic induction therapy.

resultsIn 54 patients with IBD and 30 controls, all muscle assessments correlated significantly with DXA-derived skeletal muscle index (SMI). In IBD, ultrasound of the arm and legs had the best agreement with DXA-derived SMI (mean difference 0 kg/m

conclusionsUltrasound of the arm and legs out-performed other point-of-care methods in its accuracy of measuring muscle mass. All methods, except mid-arm circumference, were responsive to therapy-induced change. Ultrasound is the preferred non-invasive test for measuring muscle mass in patients with IBD.

Indexed as

Body CompositionPoint-of-Care SystemsAbsorptiometry, PhotonAdultAnthropometryBody Mass IndexElectric ImpedanceHumansMuscle, SkeletalProspective Studies

Identifiers

PMID37305984
PMCPMC10947251

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.