Evidence map›Paper›PMID 37305917›Full record

ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2023

Selection of an anti-pathogen skin microbiome following prophylaxis treatment in an amphibian model system.

Samantha A Siomko, Sasha E Greenspan, K M Barnett, Wesley J Neely, Stanislava Chtarbanova, Douglas C Woodhams, Taegan A McMahon, C Guilherme Becker

Open access · greenAbstract read
In one paragraph

Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Advancing the study of microbial symbionts of amphibians and reptiles.Frontiers in amphibian and reptile science · 2026
    Article
  7. Probiotic colonization ofInfection and immunity · 2025
    Article
  8. Article
  9. Article
  10. Exposure toPeerJ · 2025
    Article
  11. Article
  12. Article
  13. Gene functions of theMicrobial genomics · 2024
    Article
  14. Article
  15. Selection of an anti-pathogen skin microbiome following prophylaxis treatment in an amphibian model system.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  16. Introduction to the special issue Amphibian immunity: stress, disease and ecoimmunology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Samantha A SiomkoDepartment of Biological Sciences, The University of Alabama, Tuscaloosa, AL 35487, USA.ORCID 0000-0002-0986-7191
Sasha E GreenspanDepartment of Biological Sciences, The University of Alabama, Tuscaloosa, AL 35487, USA.ORCID 0000-0001-8883-2968
K M BarnettDepartment of Biology, Emory University, Atlanta, GA 30322, USA.
Wesley J NeelyDepartment of Biological Sciences, The University of Alabama, Tuscaloosa, AL 35487, USA.ORCID 0000-0003-4563-5248
Stanislava ChtarbanovaDepartment of Biological Sciences, The University of Alabama, Tuscaloosa, AL 35487, USA.
Douglas C WoodhamsDepartment of Biology, University of Massachusetts Boston, Boston, MA 02125, USA.
Taegan A McMahonDepartment of Biology, Connecticut College, New London, CT 06320, USA.ORCID 0000-0002-0995-7445
C Guilherme BeckerDepartment of Biology, The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-5122-8238
University of Alabama · USBoston University · USDepartment of Physics, Mathematics and Informatics · BYEmory University · USPennsylvania State University · US

Funding

From specialist to generalist: biotic and abiotic reservoirs of fungal pathogensR01GM135935 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI BRIGGS, CHERYL J · 2019 to 2022
$1.6M
NIGMS NIH HHS R01 GM135935
6 · The paper itself

Abstract

With emerging diseases on the rise, there is an urgent need to identify and understand novel mechanisms of prophylactic protection in vertebrate hosts. Inducing resistance against emerging pathogens through prophylaxis is an ideal management strategy that may impact pathogens and their host-associated microbiome. The host microbiome is recognized as a critical component of immunity, but the effects of prophylactic inoculation on the microbiome are unknown. In this study, we investigate the effects of prophylaxis on host microbiome composition, focusing on the selection of anti-pathogenic microbes contributing to host acquired immunity in a model host-fungal disease system, amphibian chytridiomycosis. We inoculated larval

Indexed as

AnuraMicrobiotaAnimalsLarvaModels, BiologicalSkinacquired resistanceBatrachochytrium dendrobatidischytridiomycosishost microbiomemicrobiome memorywildlife prophylaxis

Identifiers

PMID37305917
PMCPMC10258671
OpenAlexW4380290713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.