Evidence map›Paper›PMID 37305394›Full record

ArticleOncology research2023

Multi-institutional analysis of cervical esophageal carcinoma patients treated with definitive chemoradiotherapy: TROD 01-005 study.

Ozan Cem Guler, Ezgi Oymak, Gozde Yazici, Ozlem Ozkaya Akagunduz, Oguz Cetinayak, Petek Erpolat, Atil Aksoy, Mursel Duzova, Berna Akkus Yildirim, Meral Kurt and 9 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Oncology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Overall survival after definitive chemoradiotherapy for patients with esophageal cancer: a retrospective cohort study.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 15 institutions in 1 country.

Ozan Cem GulerDepartment of Radiation Oncology, Faculty of Medicine, Baskent University, Adana Dr. Turgut Noyan Research and Treatment Center, Adana, Turkey.
Ezgi OymakRadiation Oncology Unit, Iskenderun Gelisim Hospital, Hatay, Turkey.
Gozde YaziciDepartment of Radiation Oncology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Ozlem Ozkaya AkagunduzDepartment of Radiation Oncology, Faculty of Medicine, Ege University, Izmir, Turkey.
Oguz CetinayakDepartment of Radiation Oncology, Faculty of Medicine, 9 Eylul University, Izmir, Turkey.
Petek ErpolatDepartment of Radiation Oncology, Faculty of Medicine, Gazi University, Ankara, Turkey.
Atil AksoyDepartment of Radiation Oncology, Faculty of Medicine, Akdeniz University, Antalya, Turkey.
Mursel DuzovaDepartment of Radiation Oncology, Faculty of Medicine, Selcuk University, Konya, Turkey.
Berna Akkus YildirimRadiation Oncology Unit, Prof. Dr. Cemil Tascioglu Hospital, İstanbul, Turkey.
Meral KurtDepartment of Radiation Oncology, Faculty of Medicine, Uludag University, Bursa, Turkey.
Emine CanyilmazDepartment of Radiation Oncology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Guler YavasDepartment of Radiation Oncology, Faculty of Medicine, Baskent University, Ankara, Turkey.
Serap AkyurekDepartment of Radiation Oncology, Faculty of Medicine, Ankara University, Ankara, Turkey.
Didem Colpan OksuzDepartment of Radiation Oncology, Faculty of Medicine, Istanbul University Cerrahpasa, Istanbul, Turkey.
Esra Kaytan SaglamRadiation Oncology Unit, Memorial Sisli Hospital, Istanbul, Turkey.
Omur Karakoyun CelikDepartment of Radiation Oncology, Faculty of Medicine, Celal Bayar University, Manisa, Turkey.
Enis OzyarDepartment of Radiation Oncology, Acibadem University Maslak Hospital, Istanbul, Turkey.
Mustafa CengizDepartment of Radiation Oncology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Cem OnalDepartment of Radiation Oncology, Faculty of Medicine, Baskent University, Adana Dr. Turgut Noyan Research and Treatment Center, Adana, Turkey.
Başkent University · TRHacettepe University · TRAcıbadem University · TRAkdeniz University · TRAnkara University · TRBursa Uludağ Üni̇versi̇tesi̇ · TRDokuz Eylül University · TREge University · TRGazi University · TRIstanbul Eye Hospital · TRIstanbul University-Cerrahpaşa · TRKaradeniz Technical University · TRManisa Celal Bayar University · TRMemorial Sisli Hospital · TRSelçuk University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to examine the prognostic factors and treatment outcomes of cervical esophageal carcinoma (CEC) patients who underwent definitive chemoradiotherapy (CRT). The clinical data of 175 biopsy-confirmed CEC patients treated with definitive CRT between April 2005 and September 2021 were retrospectively analyzed. The prognostic factors predicting overall survival (OS), progression-free survival (PFS), and local recurrence-free survival (LRFS) were assessed in uni- and multivariable analyses. The median age of the entire cohort was 56 years (range: 26-87 years). All patients received definitive radiotherapy with a median total dose of 60 Gy, and 52% of the patients received cisplatin-based concurrent chemotherapy. The 2-year OS, PFS, and LRFS rates were 58.8%, 46.9%, and 52.4%, respectively, with a median follow-up duration of 41.6 months. Patients' performance status, clinical nodal stage, tumor size, and treatment response were significant prognostic factors for OS, PFS, and LRFS in univariate analysis. Non-complete treatment response was an independent predictor for poor OS (HR = 4.41, 95% CI, 2.78-7.00,

Indexed as

CarcinomaEsophageal NeoplasmsUterine Cervical NeoplasmsAdultAgedAged, 80 and overChemoradiotherapyFemaleHumansMiddle AgedRetrospective StudiesChemoradiotherapyEsophageal cancerLocal controlRadiotherapySurvivalToxicity

Identifiers

PMID37305394
PMCPMC10229304
OpenAlexW4377231871

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.