Evidence map›Paper›PMID 37305219›Full record

ArticleRespiratory medicine case reports2023

Successful immunosuppressant-free treatment of a drug-induced sarcoidosis-like reaction caused by dupilumab.

Sho Saito, Masamitsu Shimizu, Ryota Miyashita, Tomoyasu Inoue, Atushiro Nagano, Shinobu Kunugi, Tsutomu Hatori, Tetsuya Okano, Masahiro Seike

Open access · goldAbstract readCase Reports
In one paragraph

Article in Respiratory medicine case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sho SaitoNippon Medical School Chiba-Hokusoh Hospital, Kamagari, Inzai, Chiba, Japan.
Masamitsu ShimizuNippon Medical School Chiba-Hokusoh Hospital, Kamagari, Inzai, Chiba, Japan.
Ryota MiyashitaNippon Medical School Chiba-Hokusoh Hospital, Kamagari, Inzai, Chiba, Japan.
Tomoyasu InoueNippon Medical School Chiba-Hokusoh Hospital, Kamagari, Inzai, Chiba, Japan.
Atushiro NaganoNippon Medical School Chiba-Hokusoh Hospital, Kamagari, Inzai, Chiba, Japan.
Shinobu KunugiDepartment of Analytic Human Pathology, Nippon Medical School, Sendagi, Bunkyo City, Tokyo, Japan.
Tsutomu HatoriDepartment of Pathology, Nippon Medical School Chiba-Hokusoh Hospital, Inzai, Chiba, Japan.
Tetsuya OkanoNippon Medical School Chiba-Hokusoh Hospital, Kamagari, Inzai, Chiba, Japan.
Masahiro SeikeDepartment of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Sendagi, Bunkyo City, Tokyo, Japan.
Chiba Hokusou Hospital · JPNippon Medical School · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of a drug-induced sarcoidosis-like reaction (DISR) in a 34-year-old female patient who had been receiving dupilumab for eosinophilic rhinosinusitis, for seven months. Computerized tomography scans revealed multiple lymphadenopathies, and biopsies performed on the lung and skin lesions showed the presence of non-caseating granulomas. The patient's serum levels of soluble interleukin-2 receptor and angiotensin-converting enzyme were elevated. There were no findings of

Indexed as

Drug-induced sarcoidosis-like reaction (DISR)DupilumabEndobronchial ultrasound transbronchial needle biopsy (EBUS-TBNA)Interleukin-13 (IL-13)Interleukin-4 (IL-4)Interleukin-5 (IL-5)Lymphadenopathy

Identifiers

PMID37305219
PMCPMC10249011
OpenAlexW4378800989

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.