Evidence map›Paper›PMID 37305041›Full record

Observational studyFrontiers in endocrinology2023

Effect of surgical treatment on patients with stage T3 or T4 triple-negative breast cancer: a SEER-based retrospective observational study.

Jie Hu, Changling Dai, Yang Zhang, Weijun Chen, Lihua Sun, Xu Zhang, Minjie Duan, Hao Fu, Teng Long, Wei Kang and 3 more

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Jie HuDepartment of Tumor Radiotherapy, Taizhou Central Hospital (Affiliated Hospital of Taizhou University), Taizhou, China.
Changling DaiDepartment of Hematology, Taizhou Central Hospital (Affiliated Hospital of Taizhou University), Taizhou, China.
Yang ZhangCollege of Medical Informatics, Chongqing Medical University, Chongqing, China.
Weijun ChenDepartment of Tumor Radiotherapy, Taizhou Central Hospital (Affiliated Hospital of Taizhou University), Taizhou, China.
Lihua SunDepartment of Tumor Radiotherapy, Taizhou Central Hospital (Affiliated Hospital of Taizhou University), Taizhou, China.
Xu ZhangSchool of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou, China.
Minjie DuanCollege of Medical Informatics, Chongqing Medical University, Chongqing, China.
Hao FuDepartment of Infectious Disease, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Teng LongDepartment of Infectious Disease, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Wei KangDepartment of Mathematics, Physics and Interdisciplinary Studies, Guangzhou Laboratory, Guangzhou, China.
Chengliang YinFaculty of Medicine, Macau University of Science and Technology, Macau, China.
Xiaozhu LiuDepartment of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jie YuDepartment of Medical Imaging, The Affiliated Taian City Central Hospital of Qingdao University, Taian, China.
Chongqing Medical University · CNTaizhou University · CNMacau University of Science and Technology · MOQingdao University · CNSecond Affiliated Hospital of Chongqing Medical University · CNTaizhou Central Hospital · CNZhejiang University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The use of surgery is controversial in patients with stage T3 or T4 triple-negative breast cancer (TNBC). We aimed to explore the effect of surgical treatment on overall survival (OS) of these patients. Methods: A total of 2,041 patients were selected and divided into the surgical and non-surgical groups based on the Surveillance, Epidemiology, and End Results database from 2010 to 2018. Propensity score matching (PSM) and inverse probability of treatment weighting (IPTW) were applied to balance covariates between different groups. The OS of the two groups were assessed by Kaplan-Meier survival curves and Cox proportional hazards regression models. Results: A total of 2,041 patients were included in the study. After PSM and IPTW, baseline characteristics of the matched variables were fully balanced. Kaplan-Meier survival curves showed that the median survival time and OS of TNBC patients with stage T3 or T4 in the surgical group were significantly improved compared with those in the non-surgical group. Multivariate Cox proportional hazards regression analysis showed that surgery was a protective factor for prognosis. Conclusion: Our study found that surgery prolonged the median survival and improved OS compared with the non-surgical group of TNBC patients with stage T3 or T4.

Indexed as

Triple Negative Breast NeoplasmsDatabases, FactualHumansKaplan-Meier EstimateMultivariate AnalysisPropensity Scoremedian survivalnon-surgical groupoverall survivalsurgical grouptriple-negative breast cancer

Identifiers

PMID37305041
PMCPMC10250696
OpenAlexW4378469342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.