Evidence map›Paper›PMID 37304851›Full record

ArticleCurrent developments in nutrition2023

Associations between the Gut Microbiota, Urinary Metabolites, and Diet in Women during the Third Trimester of Pregnancy.

Eliot N Haddad, Nikita H Nel, Lauren M Petrick, Jean M Kerver, Sarah S Comstock

Abstract read
In one paragraph

Article in Current developments in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eliot N HaddadDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA.
Nikita H NelDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA.
Lauren M PetrickDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jean M KerverDepartment of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI, USA.
Sarah S ComstockDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pregnancy causes many metabolic and physiologic changes. However, associations between gut microbiota, dietary intake, and urinary metabolites are poorly characterized in pregnant women. Objectives: The research objective was to identify dietary and microbial associations with urinary metabolites during pregnancy to elucidate potential biomarkers and microbial targets to improve maternal-fetal health. This is a secondary outcome of the study. Methods: Pregnant women ( Results: Urinary glycocholate was consistently and negatively correlated with α-carotene intake. There were 9 significant correlations between microbial taxa and urinary metabolites and 13 significant correlations between microbial taxa and dietary intake. On average, Conclusions: Several urinary metabolites and microbial taxa were associated with maternal diet and gastrointestinal community composition during the third trimester of pregnancy. Future work should determine the mechanisms underlying the associations identified herein.

Indexed as

bacteriadietgastrointestinalliquid chromatographymetabolitesmicrobiotapregnancystoolurine

Identifiers

PMID37304851
PMCPMC10257213

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.