Evidence map›Paper›PMID 37304821›Full record

ReviewFrontiers in physiology2023

SLC26 family: a new insight for kidney stone disease.

Jialin Li, Sigen Huang, Shengyin Liu, Xinzhi Liao, Sheng Yan, Quanliang Liu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jialin LiThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Sigen HuangThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Shengyin LiuThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Xinzhi LiaoThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Sheng YanThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Quanliang LiuDepartment of Urology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
First Affiliated Hospital of Gannan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The solute-linked carrier 26 (SLC26) protein family is comprised of multifunctional transporters of substrates that include oxalate, sulphate, and chloride. Disorders of oxalate homeostasis cause hyperoxalemia and hyperoxaluria, leading to urinary calcium oxalate precipitation and urolithogenesis. SLC26 proteins are aberrantly expressed during kidney stone formation, and consequently may present therapeutic targets. SLC26 protein inhibitors are in preclinical development. In this review, we integrate the findings of recent reports with clinical data to highlight the role of SLC26 proteins in oxalate metabolism during urolithogenesis, and discuss limitations of current studies and potential directions for future research.

Indexed as

hyperoxaluriakidney stoneoxalateoxalate metabolismSLC26

Identifiers

PMID37304821
PMCPMC10247987
OpenAlexW4378232728

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.