ArticleOpen veterinary journal2023
Serological and genetic diversity of hepatitis E virus among rabbits population in Egypt.
Article in Open veterinary journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- Hepatitis E Virus in the Role of an Emerging Food-Borne Pathogen.Microorganisms · 2025Review
- Uncovering the Prevalence and Genetic Characterization of Rabbit-Derived Paslahepevirus Balayani (Hepatitis E Virus) in Hebei Province, China.Food and environmental virology · 2025Article
- Zoonotic and Food-Related Hazards Due to Hepatitis A and E in Africa: A Systematic Review and Meta-Analysis.Environmental health insights · 2024Review
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Hepatitis E virus (HEV) infection has a worldwide distribution and represents an important cause of acute hepatitis. Data on rabbit HEV prevalence and genetic diversity in hyperendemic regions (Egypt) are limited, per the information on rabbit HEV's implications for human pathology. Aim: This study aimed to determine the prevalence of HEV infection in farmed rabbits from hyperendemic (Egypt) regions, as well as to examine the genetic relatedness of rabbit strains to human strains isolated in these regions. Methods: Anti-HEV was tested by ELISA from 164 serum samples isolated from rabbits in Egypt. HEV RNA was tested using reverse transcription of a nested polymerase chain reaction with degenerative primers to open reading frames 2 in feces samples from 355 farmed rabbits from Egypt (3 farms from different regions). Results: All of the animals were between the ages of 2 and 24 months. Age groups at various governorates, with the bulk of infections occurring between the ages of 2 and 12 months. HEV RNA prevalence in rabbits at the age between 2 and 12 months was varied in different governorates from 13.40%, 18.20%, and 32.10% in Qena, Luxor, and Assiut, respectively. While at the age between 12 and 24 months, HEV RNA prevalence in rabbits was 0.0%, 3.70%, and 4.30% in Assiut, Qena, and Luxor, respectively. Phylogenetic analysis did not reveal any relatedness of rabbit HEV strains neither to HEV genotype 3 sequences from patients with autochthonous hepatitis E in Egypt. Conclusion: HEV is prevalent in rabbits from Egypt with other rabbit strains belonging to species-specific group which is close to genotype 3.
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