Evidence map›Paper›PMID 37304543›Full record

ArticleTranslational cancer research2023

Identification and validation of a glycolysis-related gene signature for predicting metastasis and survival rate in patients with thyroid cancer.

Bo Wang, Yongqian Zhu, Xiang Zhang, Zijie Wang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational cancer research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Bo Wang *The Second Clinical Medical School, Nanjing Medical University, Nanjing, China.
Yongqian Zhu *Department of Medical Quality Management, the First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Xiang Zhang *Department of Urology, Affiliated Hospital of Nantong University, Nantong, China.
Zijie WangThe First Clinical Medical School, Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNAffiliated Hospital of Nantong University · CNSecond Affiliated Hospital of Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Thyroid cancer (THCA) is one of the most commonly malignant endocrine tumors worldwide. This study aimed to explore new gene signatures to better predict the metastasis and survival rate of patients with THCA. Methods: mRNA transcriptome date and clinical characteristics of THCA were obtained from the Cancer Genome Atlas (TCGA) database to identify the expression and prognostic implications of glycolysis-related genes. Gene Set Enrichment Analysis (GSEA) of differentiated expressed genes was performed, and relationship between genes and glycolysis was observed in the Cox proportional regression model. Using the cBioPortal, mutations were subsequently identified in model genes. Results: A 3-gene ( Conclusions: The study reported a three-gene signature of THCA, including

Indexed as

glycolysismetastasisprognosissurvival rateThyroid cancer (THCA)

Identifiers

PMID37304543
PMCPMC10248573
OpenAlexW4376612371

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.