Evidence map›Paper›PMID 37304416›Full record

ArticleDental research journal2023

Response of stem cells derived from human exfoliated deciduous teeth to Bio-C Repair and Mineral Trioxide Aggregate Repair HP: Cytotoxicity and gene expression assessment.

Viral Maru, Manisha Madkaikar, Ashita Gada, Vivek Pakhmode, Dimple Padawe, Salil Bapat

Open access · goldAbstract read
In one paragraph

Article in Dental research journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Viral MaruDepartment of Pediatric Dentistry, Government Dental College and Hospital, Mumbai, Maharashtra, India.
Manisha MadkaikarDirector, ICMR - National Institute of Immunohematology, Mumbai, Maharashtra, India.
Ashita GadaDirector, ICMR - National Institute of Immunohematology, Mumbai, Maharashtra, India.
Vivek PakhmodeD.M.E.R, Joint Director, SMBT Dental College, Hospital and Research Center, Mumbai, Maharashtra, India.
Dimple PadaweDepartment of Pediatric and Preventive Dentistry, Government Dental College and Hospital, Mumbai, Maharashtra, India.
Salil BapatDepartment Public Health Dentistry, SMBT Dental College, Hospital and Research Center, Mumbai, Maharashtra, India.
Government Dental College and Hospital · INICMR - National Institute of Immunohaemotology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of this study was to investigate and compare the cytotoxicity and gene expression of Bio-C Repair, Mineral Trioxide Aggregate (MTA) HP Repair, and Biodentine on stem cells derived from exfoliated deciduous teeth. Materials and Methods: In this Results: After 72 h of incubation at dilution 1:4, stem cells derived from human exfoliated deciduous teeth (SHEDs) cultivated in Biodentine, followed by Bio-C Repair and MTA Repair HP reported with highest cellular viability. The highest mRNA expression of Runx2, ALP, OCN, and DMP-1 was reported in SHEDs cultured in Biodentine (after 21 days of incubation). Conclusion: Bio-C Repair and MTA HP Repair are biocompatible and capable of odontogenic differentiation similar to Biodentine when cultured in stem cells derived from exfoliated primary teeth.

Indexed as

Bio-C Repaircytotoxicitygene expressionMineral Trioxide Aggregate HP Repairstem cells derived from human exfoliated deciduous teeth

Identifiers

PMID37304416
PMCPMC10247870
OpenAlexW4367155704

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.