Evidence map›Paper›PMID 37304305›Full record

ReviewFrontiers in immunology2023

Cell-based and cell-free immunotherapies for glioblastoma: current status and future directions.

Mingming Wang, Xiaojie Wang, Xiaoyan Jin, Jingjing Zhou, Yufu Zhang, Yiyuan Yang, Yusi Liu, Jing Zhang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mingming WangDepartment of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an, Shaanxi, China.
Xiaojie WangBasic Medical School, Shenyang Medical College, Shenyang, Liaoning, China.
Xiaoyan JinDepartment of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an, Shaanxi, China.
Jingjing ZhouDepartment of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an, Shaanxi, China.
Yufu ZhangDepartment of Hepatobiliary Surgery, the Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, China.
Yiyuan YangDepartment of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an, Shaanxi, China.
Yusi LiuDepartment of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an, Shaanxi, China.
Jing ZhangDepartment of Cell Biology and Genetics, Medical College of Yan'an University, Yan'an, Shaanxi, China.
Yan'an University · CNShenyang Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GBM) is among the most fatal and recurring malignant solid tumors. It arises from the GBM stem cell population. Conventional neurosurgical resection, temozolomide (TMZ)-dependent chemotherapy and radiotherapy have rendered the prognosis of patients unsatisfactory. Radiotherapy and chemotherapy can frequently induce non-specific damage to healthy brain and other tissues, which can be extremely hazardous. There is therefore a pressing need for a more effective treatment strategy for GBM to complement or replace existing treatment options. Cell-based and cell-free immunotherapies are currently being investigated to develop new treatment modalities against cancer. These treatments have the potential to be both selective and successful in minimizing off-target collateral harm in the normal brain. In this review, several aspects of cell-based and cell-free immunotherapies related to GBM will be discussed.

Indexed as

GlioblastomaBrainHealth StatusHumansImmunotherapyTemozolomideTemozolomidecell-based immunotherapiescell-free immunotherapiesglioblastomatemozolomidetreatment strategy

Identifiers

PMID37304305
PMCPMC10248152
OpenAlexW4378176703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.