Evidence map›Paper›PMID 37304241›Full record

ReviewOncology research2023

Progress on diagnostic and prognostic markers of pancreatic cancer.

Hong Yang, Wan Li, Liwen Ren, Yihui Yang, Yizhi Zhang, Binbin Ge, Sha Li, Xiangjin Zheng, Jinyi Liu, Sen Zhang and 4 more

Open access · hybridAbstract readReview
In one paragraph

Review in Oncology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  3. Pan-cancer characterization ofTranslational cancer research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Hong YangThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.
Wan LiThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.
Liwen RenThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.
Yihui YangThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.
Yizhi ZhangThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.
Binbin GeThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.
Sha LiThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.
Xiangjin ZhengThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.
Jinyi LiuThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.
Sen ZhangThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.
Guanhua DUThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.
B O TangDepartment of Pancreatic Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, China.
Hongquan WangDepartment of Pancreatic Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, China.
Jinhua WangThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNTianjin Medical University Cancer Institute and Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer is a malignant disease characterized by low survival and high recurrence rate, whose patients are mostly at the stage of locally advanced or metastatic disease when first diagnosed. Early diagnosis is particularly important because prognostic/predictive markers help guide optimal individualized treatment regimens. So far, CA19-9 is the only biomarker for pancreatic cancer approved by the FDA, but its effectiveness is limited by low sensitivity and specificity. With recent advances in genomics, proteomics, metabolomics, and other analytical and sequencing technologies, the rapid acquisition and screening of biomarkers is now possible. Liquid biopsy also occupies a significant place due to its unique advantages. In this review, we systematically describe and evaluate the available biomarkers that have the greatest potential as vital tools in diagnosing and treating pancreatic cancer.

Indexed as

Pancreatic NeoplasmsHumansPrognosisBiomarkersLiquid biopsyPancreatic cancerSystematic review

Identifiers

PMID37304241
PMCPMC10208033
OpenAlexW4364322402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.