Evidence map›Paper›PMID 37304070›Full record

ArticleFrontiers in molecular biosciences2023

Mass spectrometry imaging as an emerging tool for studying metabolism in human brain organoids.

Gerarda Cappuccio, Saleh M Khalil, Sivan Osenberg, Feng Li, Mirjana Maletic-Savatic

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  10. Frontiers in pharmacology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Gerarda CappuccioDepartment of Pediatrics-Neurology, Baylor College of Medicine, Houston, TX, United States.
Saleh M KhalilDepartment of Pediatrics-Neurology, Baylor College of Medicine, Houston, TX, United States.
Sivan OsenbergDepartment of Pediatrics-Neurology, Baylor College of Medicine, Houston, TX, United States.
Feng LiDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX, United States.
Mirjana Maletic-SavaticDepartment of Pediatrics-Neurology, Baylor College of Medicine, Houston, TX, United States.
Baylor College of Medicine · USNeurological Research Institute · USTexas Children's Hospital · US

Funding

Preclinical and Clincial OutcomesP50HD103555 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MIRJANA MALETIC-SAVATIC · 2020 to 2026
$9.9M
Effects of 16p11.2 copy number variation on neuronal development and pathologyR01MH130356 · NIMH · BOSTON CHILDREN'S HOSPITAL · PI MIRJANA MALETIC-SAVATIC, MUSTAFA SAHIN · 2023 to 2026
$3.2M
Elucidating Chemical Features that Block or Facilitate Passage across the Blood-Testis and/or Blood-Epidydimal Barriers in MiceR33HD099995 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI LI, FENG · 2022 to 2024
$1.7M
Elucidating Chemical Features that Block or Facilitate Passage across the Blood-Testis and/or Blood-Epidydimal Barriers in MiceR61HD099995 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI LI, FENG · 2020 to 2021
$862k
NICHD NIH HHS P50 HD103555NICHD NIH HHS R33 HD099995NICHD NIH HHS R61 HD099995NIMH NIH HHS R01 MH130356
6 · The paper itself

Abstract

Human brain organoids are emerging models to study human brain development and pathology as they recapitulate the development and characteristics of major neural cell types, and enable manipulation through an

Indexed as

brain organoidsmass spectrometry imaging methodmetabolomeneuronsneuroprogenitors

Identifiers

PMID37304070
PMCPMC10251497
OpenAlexW4377205900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.