Evidence map›Paper›PMID 37303737›Full record

ArticleOncology research2023

H1-antihistamine use and head and neck cancer risk in type 2 diabetes mellitus.

Yi-Nong Chen, Ying-Lin Chen, Wan-Ming Chen, Mingchih Chen, Ben-Chang Shia, Jenq-Yuh Ko, Szu-Yuan Wu

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yi-Nong ChenDepartment of Otorhinolaryngology, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital, Yilan, Taiwan.
Ying-Lin ChenDepartment of Otorhinolaryngology, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital, Yilan, Taiwan.
Wan-Ming ChenGraduate Institute of Business Administration, College of Management, Fu Jen Catholic University, Taipei, Taiwan.
Mingchih ChenGraduate Institute of Business Administration, College of Management, Fu Jen Catholic University, Taipei, Taiwan.
Ben-Chang ShiaGraduate Institute of Business Administration, College of Management, Fu Jen Catholic University, Taipei, Taiwan.
Jenq-Yuh KoDepartment of Otorhinolaryngology, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital, Yilan, Taiwan.
Szu-Yuan WuGraduate Institute of Business Administration, College of Management, Fu Jen Catholic University, Taipei, Taiwan.
Fu Jen Catholic University · TWLuodong Poh-Ai Hospital · TWWan Fang Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to examine the association between the use of H1-antihistamines (AHs) and head and neck cancer (HNC) risk in patients with type 2 diabetes mellitus (T2DM). Data from the National Health Insurance Research Database of Taiwan were analyzed for the period from 2008 to 2018. A propensity-score-matched cohort of 54,384 patients each in the AH user and nonuser groups was created and analyzed using Kaplan-Meier method and Cox proportional hazards regression. The results showed that the risk of HNC was significantly lower in AH users (adjusted hazard ratio: 0.55, 95% CI: 0.48 to 0.64) and the incidence rate was also lower (5.16

Indexed as

Diabetes Mellitus, Type 2Head and Neck NeoplasmsHistamine AntagonistsHumansHistamine AntagonistsH1-AntihistamineHead and neck cancerIncidenceIncidence rateType 2 diabetes

Identifiers

PMID37303737
PMCPMC10208039
OpenAlexW4322721988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.