ArticleAmerican journal of translational research2023
Application of short tandem repeat (STR) genotyping in partial hydatidiform mole.
Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
- First- and Second-Trimester Cardiovascular Anomalies in Trisomy 21 Fetuses: Anatomy, Embryology, Genetics and Imaging.Journal of personalized medicine · 2026Review
- Insights into Reproductive Immunology and Placental Pathology, 2nd Edition.International journal of molecular sciences · 2026Article
- A Partial Hydatidiform Mole in an Ovarian Ectopic Pregnancy: An Exceptional Occurrence.Diagnostics (Basel, Switzerland) · 2025Article
- Genotype Identification of Complete Hydatidiform Moles without a Maternal Component: Attempts at a Novel 26-plex STR System.Current medical science · 2025Article
- Hydatidiform Mole-Between Chromosomal Abnormality, Uniparental Disomy and Monogenic Variants: A Narrative Review.Life (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe short tandem repeat (STR) technique, which is currently the most extensively applied genetic marker, works mainly due to the differences in DNA repeats, resulting in a rich population polymorphism and high genetic stability. This paper primarily investigated the application of STR genotyping in partial hydatidiform mole (PHM).
methodsThe clinical data of 31 PHM patients and 23 hydropic abortion patients diagnosed in the Pathology Department of Beijing Tsinghua Chang Gung Hospital from 2017 to 2022 were collected and retrospectively analyzed. The histomorphological features of H&E sections were observed. Immunohistochemical staining was performed to determine p57 protein levels. STR polymorphisms (STRPs), including 15 polymorphic loci and 1 sex recognition gene locus, were detected in tissue specimens, and the role of STR in the differential diagnosis of PHM was analyzed.
resultsIn PHM cases, each STR locus of the PHM contained one maternal allele and two paternal alleles. Decidual tissue showed alleles of biparental origin. According to the Kappa's consistency test, the diagnosis made by STR showed good consistency (κ = 0.925, P < 0.001).
conclusionsSTR genotyping is of great value in the diagnosis of PHM.
Indexed as
Identifiers
37303689PMC10251018W4380290424What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.