Evidence map›Paper›PMID 37303619›Full record

ArticleAmerican journal of translational research2023

Clinical efficacy of pseudomonas aeruginosa injection combined with endostar in the treatment of malignant pleural effusion: a randomized trial.

Jianping Cheng, Xiaolin Zhao, Zhen Li, Mengyuan Yang, Yaqiong Zhang, Yang Liu, Changshi Cao

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. [Research Progress on Local Treatment of Malignant Pleural Effusion].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jianping ChengDepartment of Gastroenterology and Oncology, Civil Aviation General Hospital Beijing, The People's Republic of China.
Xiaolin ZhaoDepartment of Gastroenterology and Oncology, Civil Aviation General Hospital Beijing, The People's Republic of China.
Zhen LiDepartment of Gastroenterology and Oncology, Civil Aviation General Hospital Beijing, The People's Republic of China.
Mengyuan YangDepartment of Gastroenterology and Oncology, Civil Aviation General Hospital Beijing, The People's Republic of China.
Yaqiong ZhangDepartment of Gastroenterology and Oncology, Civil Aviation General Hospital Beijing, The People's Republic of China.
Yang LiuDepartment of Gastroenterology and Oncology, Civil Aviation General Hospital Beijing, The People's Republic of China.
Changshi CaoDepartment of Gastroenterology and Oncology, Civil Aviation General Hospital Beijing, The People's Republic of China.
Aviation General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to investigate the therapeutic effects of combining pseudomonas aeruginosa injection (PAI) with endostar on patients with malignant pleural effusion and ascites.

methodsIn this prospective study, a total of 105 patients with malignant pleural effusion and ascites admitted to our hospital from January 2019 to April 2022 were selected as research subjects. Among them, 35 patients treated with PAI combined with endostar were enrolled in the observation group, while 35 patients treated with PAI and another 35 patients treated with endostar were enrolled in the control groups. The clinical effectiveness and safety of all three groups were compared, and their relapse-free survival was examined over a period of 90 days.

resultsAfter treatment, the remission rate and the relapse-free survival of the observation group were higher than those of the control groups (

conclusionThe clinical treatment of malignant pleural effusion and ascites can be improved by combining pseudomonas aeruginosa injection with endostar. This combination can increase the relapse-free survival of patients and improve the overall safety of treatment.

Indexed as

endostarMalignant pleural effusion and ascitespseudomonas aeruginosa injectionrecombinant humanized endostatin

Identifiers

PMID37303619
PMCPMC10250978
OpenAlexW4380291351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.