Evidence map›Paper›PMID 37303381›Full record

ArticleCureus2023

Prevalence of Human Papillomavirus (HPV)-16 in Different Dental Infections in the Lebanese Population.

Wael Khalil, Ferdos Alaa El Din, Marwa Jaffal, Abd El Hadi Kanj, Ali Nabbouh, Mazen Kurban, Elias A Rahal, Ghassan M Matar

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Wael KhalilOral and Maxillofacial Surgery Department, Lebanese University, Beirut, LBN.
Ferdos Alaa El DinDepartment of Microbiology, College of Dentistry, Al-Ayen University, Thi-Qar, IRQ.
Marwa JaffalRestorative and Esthetic Dentistry, Saint Joseph University, Beirut, LBN.
Abd El Hadi KanjDepartment of Orthodontics, College of Dentistry, Al-Ayen University, Thi-Qar, IRQ.
Ali NabbouhOffice of Graduate Studies in Biomedical Sciences, American University of Beirut, Beirut, LBN.
Mazen KurbanDermatopathology, American University of Beirut Medical Center, Beirut, LBN.
Elias A RahalDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut, Beirut, LBN.
Ghassan M MatarDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut, Beirut, LBN.
Thi Qar University · IQAmerican University of Beirut · LBLebanese University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDental infections, which are the main cause of tooth loss, are known to be caused by bacteria. However, recent research suggests that other organisms, such as viruses, may also play a role. In this study, we aim to detect the presence of human papillomavirus (HPV)-16 and assess its prevalence in tissues infected with various dental infections, including aggressive and chronic periodontitis, pericoronitis, and periapical infection, as well as healthy gingival tissues, saliva, and gingival crevicular fluid, for comparison.

methodsA cross-sectional study including 124 adult healthy patients presenting with dental infections requiring dental extractions were conducted to assess the prevalence of HPV-16 in saliva, infected, and healthy tissues using quantitative polymerase chain reaction (PCR) tests. Samples were collected and a categorical scale was used for the prevalence. Statistical analyses were performed using Chi-square for the prevalence of HPV-16.

resultsAmong the HPV-16-positive PCR cases, the prevalence of HPV-16 was highest in periapical infection tissues as compared to chronic periodontitis, aggressive periodontitis, pericoronitis, and control tissues.

conclusionThe prevalence of HPV-16 in periapical infection samples was the highest among the studied dental infection samples. Thus, a primary conclusion can be drawn about the presence of an association between HPV-16 and the occurrence of periapical infection.

Indexed as

microbiologypcrperi-apical infectionpericoronitisperiodontitisvirus

Identifiers

PMID37303381
PMCPMC10251111
OpenAlexW4380291188

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.