Evidence map›Paper›PMID 37303321›Full record

ReviewCureus2023

Implications of Early Diagnosis and Intervention in the Management of Neurodevelopmental Delay (NDD) in Children: A Systematic Review and Meta-Analysis.

Sarah S Aldharman, Khalid H Al-Jabr, Yazeed S Alharbi, Nadyah K Alnajar, Jomanah J Alkhanani, Abdullrahman Alghamdi, Reem A Abdellatif, Abdullah Allouzi, Albaraa M Almallah, Syed F Jamil

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. A Review of the Effects of Maternal and Paternal Obesity on Neurodevelopmental Disorders and Related Neurobiology in Rodent and Human Offspring.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
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  12. Article
  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Sarah S AldharmanCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, SAU.
Khalid H Al-JabrCollege of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, SAU.
Yazeed S AlharbiCollege of Medicine, Qassim University, Buraydah, SAU.
Nadyah K AlnajarCollege of Medicine, Almaarefa University, Riyadh, SAU.
Jomanah J AlkhananiCollege of Medicine, Alrayan Medical College, Al-Madinah, SAU.
Abdullrahman AlghamdiCollege of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, SAU.
Reem A AbdellatifCollege of Medicine, Sulaiman Al-Rajhi University, Al Bukairiyah, SAU.
Abdullah AllouziCollege of Medicine, Sulaiman Al-Rajhi University, Al Bukairiyah, SAU.
Albaraa M AlmallahCollege of Medicine, Qassim University, Qassim, SAU.
Syed F JamilCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, SAU.
Alfaisal University · SAPrince Sattam Bin Abdulaziz University · SARoyal Commission Medical Center · SAKing Abdullah International Medical Research Center · SASulaiman Al Rajhi Colleges · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuro-developmental delay (NDD) is when a child's reflexes and nervous system are underdeveloped or immature at a given stage of child development. Neurodevelopmental delays account for delayed skill development surrounding speech, social, emotional, behavioral, motor, and cognitive delays. NDD might affect the child's psychological and physical well-being, resulting in chronic disease and disabilities throughout adulthood. This review sought to investigate the implication of early diagnosis and intervention of NDD in children. In this regard, this research opted for a systematic meta-analysis that used keywords and Boolean operators to search through main databases, including the Web of Science, JStor, PsychINFO, Science Direct, Cochrane, Scopus, and ASSIA. The result identified that telehealth interventions improved the management of NDD in children. Also, the Early Start Denver Model (ESDM) model was determined to improve the quality of life for NDD children. Another model was LEAP (Learning Experience and Alternative Program for Preschoolers and Their Parents) and Leap (Learning, engaging, and Playing), which improved behavioral, education, and social interventions in NDD children. The study identified that technology could revolutionize NDD interventions in children, possibly improving the quality of life. The parent-children relationship was shown to enhance the management of this condition; thus, it is recommended as one of the best ways to intervene in the management of NDD. Most importantly, the integration of machine learning algorithms and technology can create models; while this may not be significant in the treatment of childhood NDD but instead might be ideal in improving the quality of life for NDD children. Moreover, their social and communication skills along with academic achievements will improve. The study proposes further research in order to understand the different types of NDDs and their intervention strategies to help the researchers identify the most accurate models to improve the conditions and support the parents and guardians in the management.

Indexed as

child developmentcognitive behaviordiagnosisinterventionneurodevelopmental delay

Identifiers

PMID37303321
PMCPMC10248310
OpenAlexW4380291142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.