ArticleTropical medicine and health2023
Medicinal plants used for treatment of malaria by indigenous communities of Tororo District, Eastern Uganda.
Article in Tropical medicine and health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Traditional medicinal knowledge and diversity of medicinal plants in Benin: a systematic review (2014-2023).BMC complementary medicine and therapies · 2026Pooled it
- Ethnomedicinal Evidence for Medicinal Plants of the Asteraceae Family Used by Tanzanians to Treat Various Ailments: A Review.BioMed research international · 2026Pooled it
- The burden of malaria in East Africa: prevalence, risk factors, and control strategies.Malaria journal · 2025Pooled it
- A comprehensive review of antimalarial medicinal plants used by Tanzanians.Pharmaceutical biology · 2024Pooled it
- Diversity and perceptions about side effects of medicinal plants used by herbalists to treat gastrointestinal diseases in Sironko District, Eastern Uganda.Tropical medicine and health · 2026Article
- Nano-Enabled Herbal Remedies for Malaria Treatment: A Review of Recent Advances.Life (Basel, Switzerland) · 2026Review
- Indigenous knowledge on the uses and conservation of medicinal plants in Namutumba District, Eastern Uganda.BMC complementary medicine and therapies · 2026Article
- Indigenous knowledge and plant species used as mosquito repellents in the West Nile Subregion, Uganda.Tropical medicine and health · 2025Article
- A Review on Phytochemistry, Ethnopharmacology, and Antiparasitic Potential ofPharmaceuticals (Basel, Switzerland) · 2025Review
- Indigenous knowledge systems and malaria prevention in Zimbabwe: a market basket analysis.Malaria journal · 2025Article
- Knowledge and practices of traditional treatment of chicken diseases using medicinal plants by indigenous communities in Najjembe sub-county, Buikwe district central Uganda.BMC veterinary research · 2025Article
- Natural small molecule smart hydrogels inhibited the Hsp90/NF-κB signaling axis in inflammation to achieve sustained antipyretic effect.Journal of nanobiotechnology · 2025Article
- Medicinal plants traditionally used for management of malaria in rural communities of Uganda.BMC complementary medicine and therapies · 2025Article
- Media Composition Effects on Hairy Root Biomass and Tetrandrine Production inMolecules (Basel, Switzerland) · 2025Article
- Inhibitory Effects ofACS omega · 2024Article
- Ethnobotanical survey and phytochemistry of medicinal plants used in the management of HIV/AIDS in Eastern Uganda.Heliyon · 2024Article
- Acute and subacute toxicity profile of ethanolic stem bark extract ofToxicology reports · 2024Article
- Medicinal plants used by traditional medicine practitioners in treatment of alcohol-related disorders in Bushenyi District, southwestern Uganda.Frontiers in pharmacology · 2024Article
- Ethnomedicinal plants used for malaria treatment in Rukungiri District, Western Uganda.Tropical medicine and health · 2023Article
- The Potentials ofInfection and drug resistance · 2023Review
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundMalaria remains the leading cause of death in sub-Saharan Africa. Although recent developments such as malaria vaccine trials inspire optimism, the search for novel antimalarial drugs is urgently needed to control the mounting resistance of Plasmodium species to the available therapies. The present study was conducted to document ethnobotanical knowledge on the plants used to treat symptoms of malaria in Tororo district, a malaria-endemic region of Eastern Uganda.
methodsAn ethnobotanical study was carried out between February 2020 and September 2020 in 12 randomly selected villages of Tororo district. In total, 151 respondents (21 herbalists and 130 non-herbalists) were selected using multistage random sampling method. Their awareness of malaria, treatment-seeking behaviour and herbal treatment practices were obtained using semi-structured questionnaires and focus group discussions. Data were analysed using descriptive statistics, paired comparison, preference ranking and informant consensus factor.
resultsA total of 45 plant species belonging to 26 families and 44 genera were used in the preparation of herbal medicines for management of malaria and its symptoms. The most frequently mentioned plant species were Vernonia amygdalina, Chamaecrista nigricans, Aloe nobilis, Warburgia ugandensis, Abrus precatorius, Kedrostis foetidissima, Senna occidentalis, Azadirachta indica and Mangifera indica. Leaves (67.3%) were the most used plant part while maceration (56%) was the major method of herbal remedy preparation. Oral route was the predominant mode of administration with inconsistencies in the posology prescribed.
conclusionThis study showed that the identified medicinal plants in Tororo district, Uganda, are potential sources of new antimalarial drugs. This provides a basis for investigating the antimalarial efficacy, phytochemistry and toxicity of the unstudied species with high percentage use values to validate their use in the management of malaria.
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