Evidence map›Paper›PMID 37303065›Full record

Trial reportBMC complementary medicine and therapies2023

Effects of laughter yoga on health-related quality of life in cancer patients undergoing chemotherapy: a randomized clinical trial.

Mohammad Namazinia, Seyyed Reza Mazlum, Samira Mohajer, Violeta Lopez

3 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC complementary medicine and therapies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 23 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 6 pooled it
17.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06283810 nacompletednot on this mapstarted 2024, after this paper: background citation

The Effects of Interpersonal Relationship Psychotherapy and Laughter Therapy on Interpersonal Relationships, Problem Solving and Self-Reflection in Midwifery Students

TypeinterventionalSponsorIstanbul University - CerrahpasaRan2024 to 2024Enrolled46ConditionsMidwifery StudentsArmspsychotherapy of interpersonal relationships, laughter therapy, Plasebo
NCT06851286 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

The Effect of Laughter Therapy Given to Mothers in The Postpartum Period on Their Perceived Stress, Sleep Quality and Breastfeeding Self-Efficacy Level; Randomized Controlled Trial

TypeinterventionalSponsorSelcuk UniversityRan2025 to 2025Enrolled120ConditionsPostnatal Care, LactationArmsLaughter Therapy
NCT06917417 narecruitingnot on this mapstarted 2025, after this paper: background citation

The Effect of Laughter Therapy Given to Mothers in the Postpartum Period on Marital Adjustment, Life Satisfaction and Maternal Bonding Levels in Mothers; A Randomized Controlled Trial

TypeinterventionalSponsorSelcuk UniversityRan2025 to 2025Enrolled90ConditionsPostpartum, MothersArmsLaughter Therapy
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 6 syntheses or guidelines pooled it, 52 citations in OpenAlex.

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  6. Effects of laughter therapy on improving physical and psychological symptoms among cancer patients: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Mohammad NamaziniaDepartment of Nursing, School of Nursing and Midwifery, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran.
Seyyed Reza MazlumDepartment of Medical Surgical Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
Samira MohajerNursing and Midwifery Care Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. s_mohajer99@yahoo.com.
Violeta LopezSchool of Nursing, Midwifery and Social Sciences, Central Queensland University, Queensland, Australia. V.lopez@cqu.edu.au.
Mashhad University of Medical Sciences · IRCentral Queensland University · AUIranshahr University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChemotherapy is associated with a wide range of physical and psychological side effects, so complementary and alternative therapies may be practiced as an independent treatment or combined with the standard ones to improve health-related quality of life of cancer patients. Laughter yoga has predominantly been used as a complementary therapy to enhance health and wellbeing of ordinary people and patients with chronic diseases. However, to date, few studies have evaluated the effects of this modern exercise on cancer patients undergoing chemotherapy in clinical settings, to the best of the authors' knowledge. the present study aimed to investigate the effects of Laughter Yoga on the health-related quality of life of cancer patients undergoing chemotherapy.

methodsThis study was a two-group randomized clinical trial on 69 cancer patients undergoing chemotherapy at Reza Radiotherapy and Oncology Center, Iran in 2018. Patients were randomly divided into intervention and control groups. The intervention group received laughter yoga for four sessions at one-week intervals. Each session consists of one part and lasts for 20-30 min. Patients' health-related quality of life was assessed before and after the laughter yoga sessions using Quality of Life Questionnaire European Organization for Research and Treatment of Cancer (EORTC QLQ-C30) version 3.0. SPSS Statistics (v.20 software was used to conduct Chi-square, independent t-test, Mann-Whitney, Wilcoxon and paired t-tests analyses of the data.

resultsThe number of participants in intervention and control groups were 34 and 35, there was no significant difference of demographic and disease related characteristics and pre-intervention HRQOL between two groups. In the intervention group, there is significant difference between pre- and post-intervention scores (Mean ± Standard Deviation) of emotional functioning (12.99 ± 10.49), physical functioning (0.78 ± 6.08), role functioning (3.43 ± 7.97), fatigue (-8.82 ± 22.01), pain (-8.33 ± 11.78), sleep disturbance (-15.68 ± 18.77), and global health and quality of life (6.37 ± 5.04) (p < 0.05). There was no significant change in the control group. Participants reported no adverse events.

conclusionsA structured laughter yoga intervention in a hospital setting effectively improved health-related quality of life for cancer patients undergoing chemotherapy. Benefits to many patients could be expected if this would become a part of routine care.

trial registrationThis study was registered in the Iranian Registry of Clinical Trials (no. IRCT20180429039463N1) on 21/08/2018.

Indexed as

Laughter TherapyNeoplasmsExerciseFatigueHumansIranQuality of LifeCancer PatientsChemotherapyHealth-Related Quality of LifeLaughter yoga

Identifiers

PMID37303065
PMCPMC10259013
OpenAlexW4380271938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.