Evidence map›Paper›PMID 37303003›Full record

ArticleEuropean radiology experimental2023

Strategies for calculating contrast media dose for chest CT.

Mette Karen Henning, Catherine Gunn, Juan Arenas-Jiménez, Safora Johansen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European radiology experimental, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. [Contrast agent strategies in elective oncological imaging].Radiologie (Heidelberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 4 countries.

Mette Karen HenningFaculty of Health Sciences, Department of Life Sciences and Health, Oslo Metropolitan University, Oslo, Norway.
Catherine GunnSchool of Health Sciences, Dalhousie University, Halifax, Canada.
Juan Arenas-JiménezDepartment of Radiology, Dr. Balmis General University Hospital, Alicante, Spain.
Safora JohansenFaculty of Health Sciences, Department of Life Sciences and Health, Oslo Metropolitan University, Oslo, Norway. safora.johansen@oslomet.no.ORCID http://orcid.org/0000-0003-2307-4179
Oslo University Hospital · NODalhousie University · CAUniversitat de Miguel Hernández d'Elx · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTotal body weight (TBW) is a frequently used contrast media (CM) strategy for dose calculation in enhanced CT, yet it is suboptimal as it lacks consideration of patient characteristics, such as body fat percentage (BFP) and muscle mass. Alternative CM dosage strategies are suggested by the literature. Our objectives were to analyze the CM dose impact when adjusting to body composition using methods of obtaining lean body mass (LBM) and body surface area (BSA) along with its correlation with demographic factors in contrast enhanced chest CT examinations.

methodsEighty-nine adult patients referred for CM thoracic CT were retrospectively included, categorized as either normal, muscular, or overweight. Patient body composition data was used to calculate the CM dose according to LBM or BSA. LBM was calculated with the James method, Boer method, and bioelectric impedance (BIA). BSA was calculated using the Mostellar formula. We then correlated the corresponding CM doses with demographic factors.

resultsBIA demonstrated the highest and lowest calculated CM dose in muscular and overweight groups respectively, compared to other strategies. For the normal group, the lowest calculated CM dose was achieved using TBW. The calculated CM dose was more closely correlated with BFP using the BIA method.

conclusionsThe BIA method is more adaptive to variations in patient body habitus especially in muscular and overweight patients and is most closely correlated to patient demographics. This study could support utilizing the BIA method for calculating LBM for a body-tailored CM dose protocol for enhanced chest CT examinations. RELEVANCE STATEMENT: The BIA-based method is adaptive to variations in body habitus especially in muscular and overweight patients and is closely correlated to patient demographics for contrast-enhanced chest CT. KEY POINTS: • Calculations based on BIA showed the largest variation in CM dose. • Lean body weight using BIA demonstrated the strongest correlation to patient demographics. • Lean body weight BIA protocol may be considered for CM dosing in chest CT.

Indexed as

Contrast MediaOverweightAdultBody CompositionHumansRetrospective StudiesTomography, X-Ray ComputedContrast MediaBody compositionContrast mediaLean body weightThoraxTomography (x-ray computed)

Identifiers

PMID37303003
PMCPMC10258182
OpenAlexW4380272402

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.