Characterization of the electrocardiogram of microminipig in comparison with that of Clawn miniature swine: impacts of miniaturization of body size on electrocardiographic indices.

Ai Goto, Ryuichi Kambayashi, Hiroyuki Saito, Yasuki Akie, Hiroko Izumi-Nakaseko, Yoshinori Takei, Atsushi Sugiyama

Abstract read

In one paragraph

Article in The Journal of veterinary medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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5 · Who and what money

Authors and funding

7 authors.

Ai GotoDepartment of Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan.

Ryuichi KambayashiDepartment of Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan.

Hiroyuki SaitoDepartment of Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan.

Yasuki AkieDepartment of Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan.

Hiroko Izumi-NakasekoDepartment of Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan.

Yoshinori TakeiDepartment of Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan.

Atsushi SugiyamaDepartment of Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effects of body size reduction on electrocardiographic indices were examined using microminipigs in comparison with Clawn miniature swine (Clawn). Electrocardiogram was recorded using Holter electrocardiograph in conscious state for 24 hr for microminipigs (male: 11.6 ± 0.1 kg, 12-17 months, n=5; and female: 9.9 ± 0.4 kg, 6 months, n=5) and Clawn (female: 20.3 ± 0.4 kg, 8-9 months, n=8). Microminipig had shorter PR interval and QRS width than Clawn, whereas no significant difference was detected in JTcF/QTcF between them. Ratios of PR interval, QRS width, and body weight cubic root for microminipigs to Clawn ranged between 0.713 and 0.830. These findings indicate that PR interval and QRS width will depend on distance for excitatory current propagation, whereas JTcF/QTcF may be governed by local electrical activities.

Indexed as

ElectrocardiographySwine DiseasesAnimalsArrhythmias, CardiacBody SizeFemaleMaleMiniaturizationSwineSwine, MiniatureClawn miniature swineelectrocardiogrammicrominipigminiaturizationQT interval

Identifiers

PMID37302820

DOI10.1292/jvms.23-0049

PMCPMC10466054

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.