Evidence map›Paper›PMID 37302090›Full record

ArticleBrain structure & function2023

Reduced grey matter volume of amygdala and hippocampus is associated with the severity of autistic symptoms and language abilities in school-aged children with Autism Spectrum Disorder: an exploratory study.

Vardan Arutiunian, Elizaveta Davydova, Darya Pereverzeva, Alexander Sorokin, Svetlana Tyushkevich, Uliana Mamokhina, Kamilla Danilina, Olga Dragoy

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Article in Brain structure & function, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vardan ArutiunianCenter for Child Health, Behavior and Development, Seattle Children's Research Institute, 1920 Terry Ave., Seattle, WA, 98101, USA. vardan.arutyunyan89@gmail.com.
Elizaveta DavydovaFederal Resource Center for ASD, Moscow State University of Psychology and Education, Moscow, Russia.
Darya PereverzevaFederal Resource Center for ASD, Moscow State University of Psychology and Education, Moscow, Russia.
Alexander SorokinFederal Resource Center for ASD, Moscow State University of Psychology and Education, Moscow, Russia.
Svetlana TyushkevichFederal Resource Center for ASD, Moscow State University of Psychology and Education, Moscow, Russia.
Uliana MamokhinaFederal Resource Center for ASD, Moscow State University of Psychology and Education, Moscow, Russia.
Kamilla DanilinaFederal Resource Center for ASD, Moscow State University of Psychology and Education, Moscow, Russia.
Olga DragoyCenter for Language and Brain, HSE University, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The core symptoms of Autism Spectrum Disorder (ASD) are impairments in social interaction/communication and the presence of stereotyped and repetitive behaviour. The amygdala and hippocampus are involved in core functions in the "social brain" and, thus, may be of particular interest in ASD. Previous studies demonstrated inconsistent results, revealing both increased and reduced volume of these brain structures in individuals with ASD. In this study, we investigated the grey and white matter volumes of amygdala and hippocampus in primary-school-aged children with and without ASD. Also, we assessed the relationships between the volume of brain structures and behavioural measures in children with ASD. A total of 36 children participated in the study: 18 children with ASD (13 boys, age range 8.01-14.01 years, mean age (M

Indexed as

Autism Spectrum DisorderAutistic DisorderAdolescentAmygdalaChildGray MatterHippocampusHumansLanguageMagnetic Resonance ImagingMaleAmygdalaAutism Spectrum DisorderCommunication and languageGrey/white matter volumeHippocampus

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.