Evidence map›Paper›PMID 37301772›Full record

ArticleCancer immunology, immunotherapy : CII2023

Unbiased chemokine receptor screening reveals similar efficacy of lymph node- and tumor-targeted T cell immunotherapy.

Ludwig O Pachmayr, Anton Muehlbauer, Sophie Flommersfeld, Franziska Graml, Julian Hoenninger, Louisa von Baumgarten, Veit R Buchholz, Simon Grassmann

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ludwig O Pachmayr *Institute for Medical Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich (TUM), Munich, Germany.
Anton Muehlbauer *Institute for Medical Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich (TUM), Munich, Germany.
Sophie FlommersfeldInstitute for Medical Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich (TUM), Munich, Germany.
Franziska GramlInstitute for Medical Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich (TUM), Munich, Germany.
Julian HoenningerInstitute for Medical Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich (TUM), Munich, Germany.
Louisa von BaumgartenDepartment of Neurosurgery, Ludwigs-Maximilians-University (LMU), Munich, Germany.
Veit R Buchholz *Institute for Medical Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich (TUM), Munich, Germany. veit.buchholz@tum.de.ORCID https://orcid.org/0000-0003-0441-3913
Simon Grassmann *Institute for Medical Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich (TUM), Munich, Germany. grassmaS@mskcc.org.ORCID https://orcid.org/0000-0002-8336-3418
Technical University of Munich · DEInstitute of Medical Microbiology and Hygiene · DELudwig-Maximilians-Universität München · DEMemorial Sloan Kettering Cancer Center · US

Funding

Deutsche Forschungsgemeinschaft SFB 1054 210592381Deutsche Forschungsgemeinschaft SFB-TRR 338/1 2021-452881907Deutsche Krebshilfe 70113918
6 · The paper itself

Abstract

Localization is a crucial prerequisite for immune cell function and solid tumors evade immune control by modulating immune cell infiltration into the tumor stroma. Immunosuppressive cells like regulatory T cells are attracted, while cytotoxic CD8

Indexed as

CD8-Positive T-LymphocytesSkin NeoplasmsAnimalsHumansImmunotherapyImmunotherapy, AdoptiveLymph NodesMiceMice, Inbred C57BLReceptors, ChemokineReceptors, ChemokineAdoptive T cell therapyCancer immunotherapyChemokine receptorsSolid tumorsTumor homing

Identifiers

PMID37301772
PMCPMC10412482
OpenAlexW4380150791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.