Evidence map›Paper›PMID 37301454›Full record

ArticleEnvironmental pollution (Barking, Essex : 1987)2023

Sugarcane ash and sugarcane ash-derived silica nanoparticles alter cellular metabolism in human proximal tubular kidney cells.

Arthur D Stem, Keegan L Rogers, James R Roede, Carlos A Roncal-Jimenez, Richard J Johnson, Jared M Brown

Open access · greenAbstract read
In one paragraph

Article in Environmental pollution (Barking, Essex : 1987), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
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  8. Review
  9. American journal of physiology. Renal physiology · 2024
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Arthur D StemDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Keegan L RogersDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
James R RoedeDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Carlos A Roncal-JimenezDivision of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Richard J JohnsonDivision of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Electronic address: richard.johnson@cuanschutz.edu.
Jared M BrownDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Electronic address: jared.brown@cuanschutz.edu.
University of Colorado Anschutz Medical Campus · US

Funding

University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0M
Silica Nephropathy and Chronic Kidney Disease of Unknown EtiologyR01DK125351 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Jared Michael Brown, LEE S NEWMAN · 2020 to 2026
$4.0M
Training in Molecular and Systems ToxicologyT32ES029074 · NIEHS · UNIVERSITY OF COLORADO DENVER · PI Jared Michael Brown · 2019 to 2026
$1.1M
NCI NIH HHS P30 CA046934NIDDK NIH HHS R01 DK125351NIEHS NIH HHS T32 ES029074
6 · The paper itself

Abstract

Multiple epidemics of chronic kidney disease of an unknown etiology (CKDu) have emerged in agricultural communities around the world. Many factors have been posited as potential contributors, but a primary cause has yet to be identified and the disease is considered likely multifactorial. Sugarcane workers are largely impacted by disease leading to the hypothesis that exposure to sugarcane ash produced during the burning and harvest of sugarcane could contribute to CKDu. Estimated exposure levels of particles under 10 μm (PM

Indexed as

NanoparticlesSaccharumCell LineHumansKidneySilicon DioxideSilicon DioxideAnd kidney disease metabolismChronic kidney disease of an unknown etiologyClimateEnvironmental toxicologyHeat stressMitochondrial dysfunctionSilica nanoparticles

Identifiers

PMID37301454
PMCPMC10321436
OpenAlexW4379792570

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.