ArticleJournal of pediatric and adolescent gynecology2023
Botulinum Toxin Injections as a Treatment of Refractory Vulvodynia in Adolescents: A Case Series.
Article in Journal of pediatric and adolescent gynecology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Botulinum toxin for provoked vestibulodynia.The Cochrane database of systematic reviews · 2025Article
- A scoping review of vulvodynia research: Diagnosis, treatment, and care experiences.Women's health (London, England)Article
- Vulvar Itching and Pain Without Skin Pathology: Is Vulvodynia the Diagnosis?Pediatric dermatologyArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundVulvodynia involves vulvar discomfort that occurs in the absence of an identifiable cause. Because vulvodynia is often accompanied by myofascial pain and pelvic floor tension, transvaginal botulinum toxin (BT) injection into the pelvic floor has been proposed as a possible treatment.
methodsRetrospective case series
resultsThree adolescents with vulvodynia had a suboptimal response to treatment with several interventions, including neuromodulators (oral and topical), tricyclic antidepressants (oral and topical), and pelvic floor physical therapy. Subsequently, these patients underwent BT injections to the pelvic floor as treatment with varying responses.
conclusionIn select adolescent patients with vulvodynia, transvaginal BT injection into the pelvic floor can be an effective treatment. Further studies are needed to assess the optimal dosing, frequency, and sites of BT injections in the treatment of vulvodynia in pediatric and adolescent patients.
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