Evidence map›Paper›PMID 37300573›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2023

Hypoxia-specific imaging in patients with lymphoma undergoing CAR-T therapy.

Rahul Banerjee, Victoria Wang, Chiung-Yu Huang, Divita Pandita, Michelle K Leonard, Siobhan LaRue, Michael Ahmadi, Lawrence Kaplan, Weiyun Z Ai, Bita Fakhri and 4 more

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04409314 (Pilot Study of Hypoxia-Specific Imaging to Predict Outcomes of Chimeric Antigen Receptor T-Cell Therapy), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04409314 completednot on this map

Pilot Study of Hypoxia-Specific Imaging to Predict Outcomes of Chimeric Antigen Receptor T-Cell Therapy

TypeobservationalSponsorUniversity of California, San FranciscoRan2020 to 2023Enrolled23ConditionsRecurrent Aggressive Non-Hodgkin Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent High Grade B-Cell Lymphoma, Recurrent Malignant NeoplasmArmsFluorine F 18-fluoroazomycin Arabinoside, Positron Emission Tomography
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Rahul BanerjeeDivision of Medical Oncology, Department of Medicine, University of Washington, 825 Eastlake Ave E, LG-650, Seattle, WA, 98109, USA. rahul.banerjee.md@gmail.com.ORCID 0000-0003-3781-5441
Victoria WangDivision of Hematology and Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Chiung-Yu HuangDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
Divita PanditaDivision of Hematology and Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Michelle K LeonardDivision of Hematology and Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Siobhan LaRueDivision of Hematology and Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Michael AhmadiDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
Lawrence KaplanDivision of Hematology and Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Weiyun Z AiDivision of Hematology and Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Bita FakhriDivision of Hematology and Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Michael SpinnerDivision of Hematology and Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Madhav Rao SeshadriDivision of Hematology and Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Miguel Hernandez PampaloniDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
Charalambos Babis AndreadisDivision of Hematology and Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
University of California, San Francisco · USUniversity of Washington Medical Center · US

Funding

Mechanistic Determination of KRAS Lung Cancer Regression upon CRAF SuppressionK08CA249744 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WANG, VICTORIA · 2020 to 2025
$1.2M
Targeting Autocrine Hepatocyte Growth Factor (HGF) Production as a Therapeutic Modality in Acute Myeloid Leukemia (AML)R21CA263337 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BLASER, BRADLEY WAYNE, WANG, VICTORIA · 2023 to 2024
$415k
NCI NIH HHS K08 CA249744NCI NIH HHS R21 CA263337
6 · The paper itself

Abstract

purposeIntratumoral hypoxia in non-Hodgkin's Lymphoma (NHL) may interfere with chimeric antigen receptor T-cell (CAR-T) function. We conducted a single-center pilot study (clinicaltrials.gov ID NCT04409314) of [

methodsPatients with relapsed NHL being evaluated for CAR-T therapy received a one-time [

resultsOf 16 scanned patients, 3 had no evidence of disease by standard [

conclusionsOur pilot study identified low-level [

Indexed as

LymphomaNitroimidazolesReceptors, Chimeric AntigenAgedHumansHypoxiaMaleNeoplasm Recurrence, LocalPilot ProjectsPositron-Emission TomographyRadiopharmaceuticalsNitroimidazolesRadiopharmaceuticalsReceptors, Chimeric AntigenCAR-TFAZAHypoxiaLymphomaPET

Identifiers

PMID37300573
PMCPMC10853015
OpenAlexW4380153916

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.