ArticleJournal of cachexia, sarcopenia and muscle2023
Association between sarcopenia and frailty in elderly patients with chronic kidney disease.
Article in Journal of cachexia, sarcopenia and muscle, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
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Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association between osteosarcopenia and frailty in older adults: a systematic review and meta-analysis.BMC geriatrics · 2026Pooled it
- The effects of vivifrail-based multicomponent training on physical and cognitive function in frail older adults: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- [The Nephrogeriatrics Research Network-achieving more through interdisciplinary approaches].Innere Medizin (Heidelberg, Germany) · 2026Review
- Frailty-related factors and 1-year renal function change after sodium-glucose cotransporter-2 inhibitors in elderly chronic kidney disease patients.Kidney research and clinical practice · 2026Article
- Randomized Controlled Trial of Individualized Intervention for Frailty Reversal in Older Patients With Nondialysis CKD.Kidney international reports · 2026Article
- The association between sarcopenia and frailty in older adults: a moderated mediation model.BMC geriatrics · 2026Article
- Frailty predicts the onset and dynamic progression of cardio-renal-metabolic multimorbidity: a multistate modeling analysis from the UK Biobank.Diabetology & metabolic syndrome · 2026Article
- NSTEMI in the oldest-old: prognosis and impact of invasive management in patients ≥ 85 years.BMC geriatrics · 2026Article
- The effect of early postoperative acute pain on postoperative delirium in older persons undergoing abdominal surgery: a secondary analysis of multicenter prospective data.European geriatric medicine · 2026Article
- Increased mortality risk with lower versus higher BMI in older adults with T2DM: a Shanghai diabetes management cohort study.BMC geriatrics · 2026Article
- Calf circumference predicts sarcopenia and all-cause mortality in older patients undergoing maintenance hemodialysis: A prospective cohort study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Observational
- Frailty in Focus: A Scoping Review of Frailty Instruments from the Kidney Disease Aging Research Collaborative.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Development of a risk prediction model for dialysis access steal syndrome: exploring the interaction and modifying role of BMI.Frontiers in public health · 2026Article
- Effect of sarcopenia on risk of atrial fibrillation: a systematic review and meta-analysis of observational studies.Frontiers in cardiovascular medicine · 2026Review
- Integrating sarcopenia into ICU-acquired weakness risk stratification: a machine learning-based prediction model for critical care.Frontiers in nutrition · 2026Article
- Development and validation of a machine learning-based sarcopenia prediction model using the triglyceride glucose-frailty index.The Journal of international medical research · 2026Article
- Reclassification of chronic kidney disease in the elderly: integrating age-adjusted GFR and frailty assessment in a regional Italian population (Abruzzo).International urology and nephrology · 2026Article
- Bayesian Analysis of Frailty Risk Factors in Chronic Kidney Disease: A Nationwide Cross-Sectional Survey.Health science reports · 2026Article
- Effects of esketamine combined with QLB in older frail patients with colorectal cancer surgery.Frontiers in medicine · 2026Article
- Gender and Age-Related Decline in Lower Limb Standing Muscle Strength: Benchmarking for Rehabilitation Assessment.Sensors (Basel, Switzerland) · 2025Article
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFrailty and sarcopenia are prevalent in chronic kidney disease (CKD) populations and could increase the risk for adverse health outcomes. Few studies assess the correlation between frailty, sarcopenia and CKD in non-dialysis patients. Therefore, this study aimed to determine frailty-associated factors in elderly CKD stage I-IV patients, expected to early identify and intervene in the frailty of elderly CKD patients.
methodsA total of 774 elderly CKD I-IV patients (>60 years of age) recruited from 29 clinical centers in China between March 2017 and September 2019 were included in this study. We established a Frailty Index (FI) model to evaluate frailty risk and verified the distributional property of FI in the study population. Sarcopenia was defined according to the criteria of the Asian Working Group for Sarcopenia 2019. Multinomial logistic regression analysis was used to assess the associated factors for frailty.
resultsSeven hundred seventy-four patients (median age 67 years, 66.0% males) were included in this analysis, with a median estimated glomerular filtration rate of 52.8 mL/min/1.73 m
conclusionsSarcopenia was independently associated with an increased risk for frailty in elderly CKD I-IV patients. Patients with sarcopenia, advanced age, high CKD stage, high waist-hip ratio and low serum albumin level should be assessed for frailty.
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