Evidence map›Paper›PMID 37299969›Full record

ReviewSensors (Basel, Switzerland)2023

Machine Learning Techniques for Developing Remotely Monitored Central Nervous System Biomarkers Using Wearable Sensors: A Narrative Literature Review.

Ahnjili ZhuParris, Annika A de Goede, Iris E Yocarini, Wessel Kraaij, Geert Jan Groeneveld, Robert Jan Doll

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ahnjili ZhuParrisCentre for Human Drug Research (CHDR), Zernikedreef 8, 2333 CL Leiden, The Netherlands.ORCID 0000-0002-1413-1648
Annika A de GoedeCentre for Human Drug Research (CHDR), Zernikedreef 8, 2333 CL Leiden, The Netherlands.
Iris E YocariniLeiden Institute of Advanced Computer Science (LIACS), Snellius Gebouw, Niels Bohrweg 1, 2333 CA Leiden, The Netherlands.
Wessel KraaijLeiden Institute of Advanced Computer Science (LIACS), Snellius Gebouw, Niels Bohrweg 1, 2333 CA Leiden, The Netherlands.ORCID 0000-0001-7797-619X
Geert Jan GroeneveldCentre for Human Drug Research (CHDR), Zernikedreef 8, 2333 CL Leiden, The Netherlands.ORCID 0000-0002-4655-6667
Robert Jan DollCentre for Human Drug Research (CHDR), Zernikedreef 8, 2333 CL Leiden, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCentral nervous system (CNS) disorders benefit from ongoing monitoring to assess disease progression and treatment efficacy. Mobile health (mHealth) technologies offer a means for the remote and continuous symptom monitoring of patients. Machine Learning (ML) techniques can process and engineer mHealth data into a precise and multidimensional biomarker of disease activity.

objectiveThis narrative literature review aims to provide an overview of the current landscape of biomarker development using mHealth technologies and ML. Additionally, it proposes recommendations to ensure the accuracy, reliability, and interpretability of these biomarkers.

methodsThis review extracted relevant publications from databases such as PubMed, IEEE, and CTTI. The ML methods employed across the selected publications were then extracted, aggregated, and reviewed.

resultsThis review synthesized and presented the diverse approaches of 66 publications that address creating mHealth-based biomarkers using ML. The reviewed publications provide a foundation for effective biomarker development and offer recommendations for creating representative, reproducible, and interpretable biomarkers for future clinical trials.

conclusionmHealth-based and ML-derived biomarkers have great potential for the remote monitoring of CNS disorders. However, further research and standardization of study designs are needed to advance this field. With continued innovation, mHealth-based biomarkers hold promise for improving the monitoring of CNS disorders.

Indexed as

TelemedicineWearable Electronic DevicesBiomarkersCentral Nervous SystemHumansMachine LearningReproducibility of ResultsBiomarkersbiomarkercentral nervous systemclinical trialsmachine learningmHealthremote monitoringsmartphoneswearables

Identifiers

PMID37299969
PMCPMC10256016

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.