Evidence map›Paper›PMID 37299585›Full record

Trial reportNutrients2023

The Impact of Infant Feeding Regimen on Cow's Milk Protein Allergy, Atopic Dermatitis and Growth in High-Risk Infants during the First 6 Months of Life: The Allergy Reduction Trial.

Theodora Boutsikou, Mikaela Sekkidou, Eva Karaglani, Adamantia Krepi, George Moschonis, Nicolaos Nicolaou, Nicoletta Iacovidou, Rouzha Pancheva, Miglena Marinova-Achkar, Simoneta Popova and 9 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. [Risk factors for cow's milk protein allergy in infants: a multicenter prospective nested case-control study].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 9 institutions in 5 countries.

Theodora BoutsikouNeonatal Department, Medical School, National and Kapodistrian University of Athens, Aretaieio Hospital, 11528 Athens, Greece.
Mikaela SekkidouAsthma and Allergy Center, 3025 Limassol, Cyprus.
Eva KaraglaniDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 70 El. Venizelou Ave., 17671 Athens, Greece.ORCID 0000-0001-5395-7023
Adamantia KrepiNeonatal Department, Medical School, National and Kapodistrian University of Athens, Aretaieio Hospital, 11528 Athens, Greece.
George MoschonisDepartment of Food, Nutrition and Dietetics, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, VIC 3086, Australia.ORCID 0000-0003-3009-6675
Nicolaos NicolaouAsthma and Allergy Center, 3025 Limassol, Cyprus.
Nicoletta IacovidouNeonatal Department, Medical School, National and Kapodistrian University of Athens, Aretaieio Hospital, 11528 Athens, Greece.ORCID 0000-0001-8021-6191
Rouzha PanchevaDepartment of Hygiene and Epidemiology, Faculty of Public Health, Medical University of Varna, 9000 Varna, Bulgaria.ORCID 0000-0001-8286-3923
Miglena Marinova-AchkarDepartment of Hygiene and Epidemiology, Faculty of Public Health, Medical University of Varna, 9000 Varna, Bulgaria.
Simoneta PopovaDepartment of Hygiene and Epidemiology, Faculty of Public Health, Medical University of Varna, 9000 Varna, Bulgaria.
Anastasia KapetanakiNeonatal Intensive Care Unit, General and Maternity Hospital Elena Venizelou, 11521 Athens, Greece.
Zoi IliodromitiNeonatal Department, Medical School, National and Kapodistrian University of Athens, Aretaieio Hospital, 11528 Athens, Greece.ORCID 0000-0003-4316-7305
Vassiliki PapaevangelouThird Department of Pediatrics, National and Kapodistrian University of Athens, ATTIKON General University Hospital, 12462 Athens, Greece.
Olympia SardeliThird Department of Pediatrics, National and Kapodistrian University of Athens, ATTIKON General University Hospital, 12462 Athens, Greece.
Evangelia PapathomaNeonatal Intensive Care Unit, Alexandra General Hospital, 11528 Athens, Greece.
Anne SchaafsmaFrieslandCampina, 3818 LE Amersfoort, The Netherlands.
Rolf BosFrieslandCampina, 3818 LE Amersfoort, The Netherlands.
Yannis ManiosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 70 El. Venizelou Ave., 17671 Athens, Greece.ORCID 0000-0001-6486-114X
Paraskevi XepapadakiAllergy Department, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, 15771 Athens, Greece.ORCID 0000-0001-9204-1923
National and Kapodistrian University of Athens · GRMedical University of Varna · BGFrieslandCampina (Netherlands) · NLUniversity of Nicosia · CYAlexandra Hospital · GRGeneral-Maternity District Hospital Helena Venizelou · GRHarokopio University of Athens · GRHellenic Mediterranean University · GRLa Trobe University · AU

Funding

FrieslandCampina Nederland B.V N/A
6 · The paper itself

Abstract

The development of early-onset cow's milk protein allergy and atopic dermatitis during the first months of life is multifactorial, including both genetic and nutritional aspects. This study aims to assess the impact of different feeding patterns on the incidence of cow's milk protein allergy, atopic dermatitis, and growth among infants with a family history of allergy. A total of 551 high-risk infants were randomly recruited from 3 European countries in three feeding regimens: exclusive breastfeeding, partially hydrolyzed formula, or standard formula with intact protein either exclusively or supplementary to breastfeeding. During the first 6 months of intervention, amongst infants with a family history of atopic dermatitis, 6.5% of partially hydrolyzed formula-fed infants and 22.7% of exclusively breastfed infants (

Indexed as

Dermatitis, AtopicMilk HypersensitivityAllergensAnimalsCattleFemaleHumansInfantInfant FormulaInfant, NewbornMilk, HumanMilk ProteinsAllergensMilk Proteinsatopic dermatitisbreastfed infantscow’s milk protein allergyhydrolyzed formula

Identifiers

PMID37299585
PMCPMC10255921
OpenAlexW4379386245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.