Evidence map›Paper›PMID 37299581›Full record

ArticleNutrients2023

The Effect of a Low-Carbohydrate High-Fat Diet on Laboratory Parameters in Women with Lipedema in Comparison to Overweight/Obese Women.

Małgorzata Jeziorek, Andrzej Szuba, Monika Sowicz, Agnieszka Adaszyńska, Krzysztof Kujawa, Angelika Chachaj

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
9.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Małgorzata JeziorekDepartment of Dietetics and Bromatology, Faculty of Pharmacy, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Andrzej SzubaDepartment of Angiology, Hypertension and Diabetology, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Monika SowiczDepartment of Angiology, Hypertension and Diabetology, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Agnieszka AdaszyńskaDepartment of Angiology, Hypertension and Diabetology, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Krzysztof KujawaStatistical Analysis Center, Wroclaw Medical University, 50-367 Wroclaw, Poland.ORCID 0000-0003-2812-4702
Angelika ChachajDepartment of Angiology, Hypertension and Diabetology, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Wroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate alterations in blood parameters after a low-carbohydrate high-fat (LCHF) diet in women with lipedema in comparison to overweight or obese women. A total of 115 women were classified into two groups: the lipedema group and the overweight/obesity group. Both study groups followed the caloric-restricted LCHF diet for 7 months. A total of 48 women completed the study. A reduction in body weight was observed in both study groups. A significant decrease in triglycerides and an increase in HDL-C concentrations were observed in both study groups. Despite the increase in the concentration of LDL-C observed in the lipedema group, changes in LDL-C differed between individual patients. Improvements in liver parameters, glucose tolerance, and a decrease in fasting insulin levels were observed, although they were less pronounced in the lipedema group than in the overweight/obesity group. Kidney and thyroid functions were similar before and after the LCHF diet in both groups. The LCHF diet may be a valuable nutritional strategy for lipedema and overweight/obese women, with a beneficial effect on weight, glucose profile, liver function, the concentration of triglycerides, and HDL-C and with no effect on kidney and thyroid function.

Indexed as

LipedemaOverweightCarbohydratesCholesterol, LDLDiet, Carbohydrate-RestrictedDiet, High-FatFemaleGlucoseHumansObesityTriglyceridesWeight LossCarbohydratesCholesterol, LDLGlucoseTriglyceridesblood parameterslipedemalow-carbohydrate high-fat dietobesity

Identifiers

PMID37299581
PMCPMC10255157
OpenAlexW4379233079

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.