Evidence map›Paper›PMID 37299550›Full record

ArticleNutrients2023

Probiotics and Human Milk Differentially Influence the Gut Microbiome and NEC Incidence in Preterm Pigs.

Valeria Melendez Hebib, Diana H Taft, Barbara Stoll, Jinxin Liu, Lee Call, Gregory Guthrie, Nick Jensen, Amy B Hair, David A Mills, Douglas G Burrin

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 9 citations in OpenAlex.

  1. Necrotizing enterocolitis.Nature reviews. Disease primers · 2026
    Review
  2. Article
  3. Review
  4. Perinatal and laboratory determinants of fortified human milk use: a case-control study.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Article
  5. Article
  6. Article
  7. Antioxidants (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Valeria Melendez HebibUSDA Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Diana H TaftFoods for Health Institute, University of California, Davis, CA 95616, USA.
Barbara StollUSDA Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Jinxin LiuFoods for Health Institute, University of California, Davis, CA 95616, USA.ORCID 0000-0002-5302-866X
Lee CallUSDA Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Gregory GuthrieUSDA Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0001-7644-9582
Nick JensenFoods for Health Institute, University of California, Davis, CA 95616, USA.
Amy B HairSection of Neonatology, Departments of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX 77030, USA.ORCID 0000-0001-7570-0667
David A MillsFoods for Health Institute, University of California, Davis, CA 95616, USA.ORCID 0000-0003-1913-9865
Douglas G BurrinUSDA Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Children's Nutrition Research Center at Baylor College of Medicine · USUniversity of California, Davis · USBaylor College of Medicine · USNanjing Agricultural University · CN

Funding

Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Geoffrey A Preidis · 2001 to 2026
$28.3M
TRAINING PROGRAM IN COMPUTATIONAL BIOLOGY AND MEDICINET15LM007093 · NLM · RICE UNIVERSITY · PI Lydia E. Kavraki · 1992 to 2026
$20.8M
Training Program in Translational Biology and Molecular MedicineT32GM088129 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI ROONEY, CLIONA M., VAN DEN VEYVER, IGNATIA B · 2010 to 2019
$3.0M
The Clinical Translational Research Certificate of Added Qualification ProgramT32GM136554 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI Melissa Suter, IGNATIA B VAN DEN VEYVER · 2020 to 2026
$3.0M
Mechanism of Activation of Probiotic Bifidobacteria by Prebiotic Milk GlycansR01AT007079 · NCCIH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GERMAN, BRUCE, LEBRILLA, CARLITO B · 2012 to 2016
$2.2M
Effects of Bifidobacterium Dominance on the Infant MicrobiomeF32HD093185 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI TAFT, DIANA HAZARD · 2017 to 2020
$218k
NCCIH NIH HHS R01 AT007079NICHD NIH HHS F32 HD093185NIDDK NIH HHS P30 DK056338NIGMS NIH HHS T32 GM088129NIGMS NIH HHS T32 GM136554NIH HHS F32HD093185NIH HHS P30 DK-56338NIH HHS R01AT007079NIH HHS T32-GM088129NIH HHS T32GM136554NLM NIH HHS T15 LM007093
6 · The paper itself

Abstract

Necrotizing enterocolitis (NEC) is the leading cause of death caused by gastrointestinal disease in preterm infants. Major risk factors include prematurity, formula feeding, and gut microbial colonization. Microbes have been linked to NEC, yet there is no evidence of causal species, and select probiotics have been shown to reduce NEC incidence in infants. In this study, we evaluated the effect of the probiotic

Indexed as

Enterocolitis, NecrotizingGastrointestinal MicrobiomeProbioticsAnimalsBifidobacterium longum subspecies infantisHumansIncidenceMilk, HumanSwineBifidobacterium longum subsp. infantisClostridium perfringensClostridium sensu stricto 1human milkhuman milk oligosaccharidemicrobiomenecrotizing enterocolitispremature infant

Identifiers

PMID37299550
PMCPMC10255242
OpenAlexW4379053648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.