Evidence map›Paper›PMID 37299538›Full record

ArticleNutrients2023

Preparation of Red Ginseng Marc-Derived Gintonin and Its Application as a Skin Nutrient.

Rami Lee, Ji-Hun Kim, Hongik Hwang, Hyewhon Rhim, Sung-Hee Hwang, Ik-Hyun Cho, Do-Geun Kim, Hyoung-Chun Kim, Seung-Yeol Nah

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Rami LeeGinsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0002-0179-7563
Ji-Hun KimGinsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0002-5751-7014
Hongik HwangDepartment of Life Science, University of Seoul, Seoul 02504, Republic of Korea.ORCID 0000-0002-6363-9579
Hyewhon RhimCenter for Neuroscience, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.
Sung-Hee HwangDepartment of Pharmaceutical Engineering, College of Health Sciences, Sangji University, Wonju 26339, Republic of Korea.
Ik-Hyun ChoDepartment of Convergence Korean Medical Science, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.ORCID 0000-0002-1036-0494
Do-Geun KimKorea Brain Research Institute (KBRI), 61, Cheomdan-ro, Dong-gu, Daegu 41062, Republic of Korea.
Hyoung-Chun KimNeuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon 24341, Republic of Korea.ORCID 0000-0003-0420-795X
Seung-Yeol NahGinsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0001-9697-4763
Konkuk University · KRKangwon National University · KRKorea Brain Research Institute · KRKorea Institute of Science and Technology · KRKyung Hee University · KRSangji University · KRUniversity of Seoul · KR

Funding

The Korean government (MSIT) 2023R1A2C1003481
6 · The paper itself

Abstract

Ginseng is one of the traditional herbal medicines for tonic. Gintonin is a new material derived from white/red ginseng and its lysophosphatidic acids (LPAs) play as a ligand for G protein-coupled LPA receptors. Korean red ginseng marc (KRGM) is a by-product after the KRG processes. We developed a low-cost/high-efficiency method for KRGM gintonin production. We further studied the KRGM gintonin-mediated anti-skin aging effects under UVB exposure using human dermal fibroblasts (HDFs). KRGM gintonin yield is about 8%. KRGM gintonin contains a high amount of LPA C

Indexed as

PanaxPlant ExtractsHumansNutrientsReceptors, G-Protein-CoupledgintoninNutrientsPlant ExtractsReceptors, G-Protein-CoupledcosmeticsgintoninKorean red ginseng marcLPA receptorsskin damage

Identifiers

PMID37299538
PMCPMC10255325
OpenAlexW4378903174

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.