Evidence map›Paper›PMID 37299492›Full record

ReviewNutrients2023

Relationship between Gut Microbiota and Allergies in Children: A Literature Review.

Alexandru Cosmin Pantazi, Cristina Maria Mihai, Adriana Luminita Balasa, Tatiana Chisnoiu, Ancuta Lupu, Corina Elena Frecus, Larisia Mihai, Adina Ungureanu, Mustafa Ali Kassim Kassim, Antonio Andrusca and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  8. Gut Microbiota Modulation in Asthma-An In Vitro Study.Pharmaceuticals (Basel, Switzerland) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Alexandru Cosmin PantaziPediatrics, Faculty of General Medicine, "Ovidius" University, 900470 Constanta, Romania.ORCID 0000-0002-7234-2814
Cristina Maria MihaiPediatrics, Faculty of General Medicine, "Ovidius" University, 900470 Constanta, Romania.ORCID 0000-0001-8844-0593
Adriana Luminita BalasaPediatrics, Faculty of General Medicine, "Ovidius" University, 900470 Constanta, Romania.
Tatiana ChisnoiuPediatrics, Faculty of General Medicine, "Ovidius" University, 900470 Constanta, Romania.ORCID 0000-0002-4996-2484
Ancuta LupuPediatrics, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0001-8147-3632
Corina Elena FrecusPediatrics, Faculty of General Medicine, "Ovidius" University, 900470 Constanta, Romania.
Larisia MihaiPediatrics, Faculty of General Medicine, "Ovidius" University, 900470 Constanta, Romania.
Adina UngureanuPediatrics, Faculty of General Medicine, "Ovidius" University, 900470 Constanta, Romania.
Mustafa Ali Kassim KassimFaculty of General Medicine, "Ovidius" University, 900470 Constanta, Romania.
Antonio AndruscaPediatrics, Faculty of General Medicine, "Ovidius" University, 900470 Constanta, Romania.
Maria NicolaePediatrics, Faculty of General Medicine, "Ovidius" University, 900470 Constanta, Romania.
Viviana CuzicPediatrics, Faculty of General Medicine, "Ovidius" University, 900470 Constanta, Romania.
Vasile Valeriu LupuPediatrics, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0003-2640-8795
Simona Claudia CambreaInfectious Diseases, Faculty of General Medicine, "Ovidius" University, 900470 Constanta, Romania.ORCID 0000-0003-4898-8938
Ovidius University · ROGrigore T. Popa University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intestinal microbiota is a diverse and complex microecosystem that lives and thrives within the human body. The microbiota stabilizes by the age of three. This microecosystem plays a crucial role in human health, particularly in the early years of life. Dysbiosis has been linked to the development of various allergic diseases with potential long-term implications. Next-generation sequencing methods have established that allergic diseases are associated with dysbiosis. These methods can help to improve the knowledge of the relationship between dysbiosis and allergic diseases. The aim of this review paper is to synthesize the current understanding on the development of the intestinal microbiota in children, the long-term impact on health, and the relationship between dysbiosis and allergic diseases. Furthermore, we examine the connection between the microbiome and specific allergies such as atopic dermatitis, asthma, and food allergies, and which mechanisms could determine the induction of these diseases. Furthermore, we will review how factors such as mode of delivery, antibiotic use, breastfeeding, and the environment influence the development of the intestinal flora, as well as review various interventions for the prevention and treatment of gut microbiota-related allergies.

Indexed as

AsthmaDermatitis, AtopicFood HypersensitivityGastrointestinal MicrobiomeChildDysbiosisHumansallergyasthmaatopic dermatitischildrenfood allergymicrobiota

Identifiers

PMID37299492
PMCPMC10255222
OpenAlexW4378717987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.