Evidence map›Paper›PMID 37299355›Full record

ArticlePolymers2023

Development of a Water Transmission Rate (WTR) Measurement System for Implantable Barrier Coatings.

Sébastien Buchwalder, Cléo Nicolier, Mario Hersberger, Florian Bourgeois, Andreas Hogg, Jürgen Burger

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sébastien BuchwalderSchool of Biomedical and Precision Engineering, University of Bern, Güterstrasse 24/26, 3010 Bern, Switzerland.ORCID 0000-0003-4828-2265
Cléo NicolierSchool of Biomedical and Precision Engineering, University of Bern, Güterstrasse 24/26, 3010 Bern, Switzerland.ORCID 0000-0003-1816-5156
Mario HersbergerSchool of Biomedical and Precision Engineering, University of Bern, Güterstrasse 24/26, 3010 Bern, Switzerland.
Florian BourgeoisCoat-X SA, Eplatures-Grise 17, 2300 La Chaux-de-Fonds, Switzerland.
Andreas HoggCoat-X SA, Eplatures-Grise 17, 2300 La Chaux-de-Fonds, Switzerland.
Jürgen BurgerSchool of Biomedical and Precision Engineering, University of Bern, Güterstrasse 24/26, 3010 Bern, Switzerland.ORCID 0000-0003-2496-638X
University of Bern · CH

Funding

Innosuisse - Swiss Innovation Agency 41363.1 IP-LS
6 · The paper itself

Abstract

While water vapor transmission rate (WVTR) measurement is standardly used to assess material permeability, a system able to quantify liquid water transmission rate (WTR) measurement is highly desirable for implantable thin film barrier coatings. Indeed, since implantable devices are in contact or immersed in body fluids, liquid WTR was carried out to obtain a more realistic measurement of the barrier performance. Parylene is a well-established polymer which is often the material of choice for biomedical encapsulation applications due to its flexibility, biocompatibility, and attractive barrier properties. Four grades of parylene coatings were tested with a newly developed permeation measurement system based on a quadrupole mass spectrometer (QMS) detection method. Successful measurements of gas and water vapor and the water transmission rates of thin parylene films were performed and validated, comparing the results with a standardized method. In addition, the WTR results allowed for the extraction of an acceleration transmission rate factor from the vapor-to-liquid water measurement mode, which varies from 4 to 4.8 between WVTR and WTR. With a WTR of 72.5 µm g m

Indexed as

barrier coatingsbiomedical encapsulationgas transmission rate (GTR)parylenewater transmission rate (WTR)water vapor transmission rate (WVTR)

Identifiers

PMID37299355
PMCPMC10255625
OpenAlexW4379230536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.