Evidence map›Paper›PMID 37299270›Full record

ReviewPolymers2023

Additive Manufacturing of Polymer/Bioactive Glass Scaffolds for Regenerative Medicine: A Review.

Andrea Martelli, Devis Bellucci, Valeria Cannillo

Abstract readReview
In one paragraph

Review in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  5. In Vivo Study of Bone Growth Around Additively Manufactured Implants With Ti-6Al-4V and Bioactive Glass Powder Composites.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andrea MartelliDipartimento di Ingegneria Enzo Ferrari, Università degli Studi di Modena e Reggio Emilia, Via. P. Vivarelli 10, 41125 Modena, Italy.ORCID 0000-0003-0538-4480
Devis BellucciDipartimento di Ingegneria Enzo Ferrari, Università degli Studi di Modena e Reggio Emilia, Via. P. Vivarelli 10, 41125 Modena, Italy.
Valeria CannilloDipartimento di Ingegneria Enzo Ferrari, Università degli Studi di Modena e Reggio Emilia, Via. P. Vivarelli 10, 41125 Modena, Italy.ORCID 0000-0001-7161-5297

Funding

PNRR MUR project ECS_00000033_ECOSISTERUniversità degli Studi di Modena e Reggio Emilia, Italy Progetto FARD-2022 "MATLIFE"
6 · The paper itself

Abstract

Tissue engineering (TE) is a branch of regenerative medicine with enormous potential to regenerate damaged tissues using synthetic grafts such as scaffolds. Polymers and bioactive glasses (BGs) are popular materials for scaffold production because of their tunable properties and ability to interact with the body for effective tissue regeneration. Due to their composition and amorphous structure, BGs possess a significant affinity with the recipient's tissue. Additive manufacturing (AM), a method that allows the creation of complex shapes and internal structures, is a promising approach for scaffold production. However, despite the promising results obtained so far, several challenges remain in the field of TE. One critical area for improvement is tailoring the mechanical properties of scaffolds to meet specific tissue requirements. In addition, achieving improved cell viability and controlled degradation of scaffolds is necessary to ensure successful tissue regeneration. This review provides a critical summary of the potential and limitations of polymer/BG scaffold production via AM covering extrusion-, lithography-, and laser-based 3D-printing techniques. The review highlights the importance of addressing the current challenges in TE to develop effective and reliable strategies for tissue regeneration.

Indexed as

additive manufacturingbioactive glasscompositepolymerscaffoldtissue engineering

Identifiers

PMID37299270
PMCPMC10255145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.