ArticleMolecules (Basel, Switzerland)2023
Group I Intron as a Potential Target for Antifungal Compounds: Development of a
Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Baseline Sensitivity of Botryosphaeria spp. Isolated from Apples to Pyraclostrobin in Korea.The plant pathology journal · 2025Article
- Enhanced hammerhead ribozyme turnover rates: Reevaluating therapeutic space for small catalytic RNAs.Molecular therapy. Nucleic acids · 2025Article
- Group I introns: Structure, splicing and their applications in medical mycology.Genetics and molecular biology · 2024Article
- The mitogenomes ofFrontiers in microbiology · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The search for safe and efficient new antifungal compounds for agriculture has led to more efforts in finding new modes of action. This involves the discovery of new molecular targets, including coding and non-coding RNA. Rarely found in plants and animals but present in fungi, group I introns are of interest as their complex tertiary structure may allow selective targeting using small molecules. In this work, we demonstrate that group I introns present in phytopathogenic fungi have a self-splicing activity in vitro that can be adapted in a high-throughput screening to find new antifungal compounds. Ten candidate introns from different filamentous fungi were tested and one group ID intron found in
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Registered trials
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