Evidence map›Paper›PMID 37298918›Full record

ArticleMolecules (Basel, Switzerland)2023

Separation of Flavonoids and Purification of Chlorogenic Acid from Bamboo Leaves Extraction Residues by Combination of Macroporous Resin and High-Speed Counter-Current Chromatography.

Yifeng Zhou, Meixu Chen, Xinyi Huo, Qilin Xu, Linlin Wu, Liling Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yifeng ZhouSchool of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, China.
Meixu ChenSchool of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, China.
Xinyi HuoSchool of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, China.
Qilin XuSchool of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, China.
Linlin WuSchool of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, China.
Liling WangZhejiang Academy of Forestry, Hangzhou 310023, China.

Funding

Zhejiang Provincial Public Welfare Technology Application and Research Project of China LGN21C020004
6 · The paper itself

Abstract

Flavonoids are major active small-molecule compounds in bamboo leaves, which can be easily obtained from the bamboo leaves extraction residues (BLER) after the polysaccharides extraction. Six macroporous resins with different properties were screened to prepare and enrich isoorientin (IOR), orientin (OR), vitexin (VI), and isovitexin (IVI) from BLER, and the XAD-7HP resin with the best adsorption and desorption performance was selected for further evaluation. Based on the static adsorption experiments, the experimental results showed that the adsorption isotherm fitted well with the Langmuir isotherm model, and the adsorption process was better explained by the pseudo-second-order kinetic model. After the dynamic trial of resin column chromatography, 20 bed volume (BV) of upload sample and 60% ethanol as eluting solvent was used in a lab scale-up separation, and the results demonstrated that the content of four flavonoids could be increased by 4.5-fold, with recoveries between 72.86 and 88.21%. In addition, chlorogenic acid (CA) with purity of 95.1% was obtained in water-eluted parts during dynamic resin separation and further purified by high-speed countercurrent chromatography (HSCCC). In conclusion, this rapid and efficient method can provide a reference to utilize BLER to produce high-value-added food and pharmaceutical products.

Indexed as

Chlorogenic AcidCountercurrent DistributionAdsorptionChromatography, High Pressure LiquidFlavonoidsPlant ExtractsPlant LeavesResins, PlantResins, SyntheticChlorogenic AcidFlavonoidsPlant ExtractsResins, PlantResins, Syntheticbamboo leaveschlorogenic acid (CA)flavonoidshigh-speed countercurrent chromatography (HSCCC)macroporous resin

Identifiers

PMID37298918
PMCPMC10254542

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.