Evidence map›Paper›PMID 37298744›Full record

ArticleMolecules (Basel, Switzerland)2023

Optimization and Antibacterial Evaluation of Novel 3-(5-Fluoropyridine-3-yl)-2-oxazolidinone Derivatives Containing a Pyrimidine Substituted Piperazine.

Xin Wang, Bo Jin, Yutong Han, Tong Wang, Zunlai Sheng, Ye Tao, Hongliang Yang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Recent Advances in Pyrimidine-Based Drugs.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xin WangDepartment of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China.
Bo JinDepartment of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China.ORCID 0000-0002-1365-0657
Yutong HanDepartment of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China.
Tong WangDepartment of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China.
Zunlai ShengDepartment of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China.
Ye TaoDepartment of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China.
Hongliang YangDepartment of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China.
Northeast Agricultural University · CN

Funding

National Natural Science Foundation of China No. 31802227
6 · The paper itself

Abstract

In this study, a series of novel 3-(5-fluoropyridine-3-yl)-2-oxazolidinone derivatives were designed and synthesized based on compounds previously reported, and their antibacterial activity was investigated. Then their antibacterial activity was investigated for the first time. Preliminary screening results showed that all these compounds exhibited antibacterial activity against gram-positive bacteria, including 7 drug-sensitive strains and 4 drug-resistant strains, among which compound

Indexed as

OxazolidinonesAnti-Bacterial AgentsGram-Positive BacteriaMicrobial Sensitivity TestsMolecular Docking SimulationMolecular StructureOxindolesPiperazinePyrimidinesStructure-Activity RelationshipAnti-Bacterial AgentsOxazolidinonesOxindolesPiperazinePyrimidines3-(5-fluoropyridine-3-yl)-2-oxazolidinone derivativesantibacterial activityantibiofilm activitydrug resistancemolecular docking

Identifiers

PMID37298744
PMCPMC10254757
OpenAlexW4378082622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.