ReviewInternational journal of molecular sciences2023
Human Placental Adaptive Changes in Response to Maternal Obesity: Sex Specificities.
Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Molecular Mechanisms of Obesity-Associated Oxidative Stress and Therapeutic Strategies.Antioxidants (Basel, Switzerland) · 2026Review
- Association Between Relative Cord Hyperleptinemia and Offspring Outcomes in Pregnant Women With Overweight or Obesity.Pediatric obesity · 2026Article
- Maternal Obesity Modulates Postpartum Inflammatory and Hormonal Profiles, Without Detectable Differences in Tested Redox Markers.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Observational
- Maternal obesity shapes associations between preeclampsia and birthweight in pregnancies exposed to low-dose aspirin.Frontiers in physiology · 2026Article
- Unraveling the complex web: pathogenesis and prevention of gestational diabetes mellitus-related fetal overgrowth.Frontiers in cell and developmental biology · 2026Review
- Liver as a metabolic sensor in gestational diabetes: Implications for offspring's liver and diabetes risk.World journal of hepatology · 2025Review
- Placental Morphology and Metabolomic Profile in Uncomplicated Metabolically Healthy Obese Pregnancy.Biomedicines · 2025Article
- Maternal Obesity Alters Placental and Umbilical Cord Plasma Oxidative Stress, a Cross-Sectional Study.International journal of molecular sciences · 2024Article
- Placental pathology and fetal growth outcomes in pregnancies complicated by maternal obesity.International journal of obesity (2005) · 2024Article
- High-throughput mRNA sequencing of human placenta shows sex differences across gestation.Placenta · 2024Article
- Placental pathology and neonatal morbidity: exploring the impact of gestational age at birth.BMC pregnancy and childbirth · 2024Observational
- Fetal sexual dimorphism of maternal thyroid function parameters during pregnancy, a single center retrospective real-world study.Frontiers in endocrinology · 2024Article
- Role of Oxidative Stress and Inflammation in Gestational Diabetes Mellitus.Antioxidants (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maternal obesity is increasingly prevalent and is associated with elevated morbidity and mortality rates in both mothers and children. At the interface between the mother and the fetus, the placenta mediates the impact of the maternal environment on fetal development. Most of the literature presents data on the effects of maternal obesity on placental functions and does not exclude potentially confounding factors such as metabolic diseases (e.g., gestational diabetes). In this context, the focus of this review mainly lies on the impact of maternal obesity (in the absence of gestational diabetes) on (i) endocrine function, (ii) morphological characteristics, (iii) nutrient exchanges and metabolism, (iv) inflammatory/immune status, (v) oxidative stress, and (vi) transcriptome. Moreover, some of those placental changes in response to maternal obesity could be supported by fetal sex. A better understanding of sex-specific placental responses to maternal obesity seems to be crucial for improving pregnancy outcomes and the health of mothers and children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.