Evidence map›Paper›PMID 37298700›Full record

ReviewInternational journal of molecular sciences2023

Etiopathogenesis and Emerging Methods for Treatment of Vitiligo.

Tomasz Iwanowski, Karol Kołkowski, Roman Janusz Nowicki, Małgorzata Sokołowska-Wojdyło

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Screening for Biomarkers Related to Pigmentation and Formation in Vitiligo.Combinatorial chemistry & high throughput screening · 2025
    Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Vitiligo: Clinical and Laboratory Characteristics in 573 Saudi Patients.Clinical, cosmetic and investigational dermatology · 2024
    Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tomasz IwanowskiDermedica, Aleja Zwycięstwa 34, 80-219 Gdansk, Poland.ORCID 0009-0006-6944-1383
Karol KołkowskiDermatological Students Scientific Association, Department of Dermatology, Venerology and Allergology, Faculty of Medicine, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0000-0001-5977-2126
Roman Janusz NowickiDepartment of Dermatology, Venerology and Allergology, Faculty of Medicine, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0000-0003-4768-1387
Małgorzata Sokołowska-WojdyłoDepartment of Dermatology, Venerology and Allergology, Faculty of Medicine, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0000-0002-7626-3689
Gdańsk Medical University · PL

Funding

Polish Ministry of Science and Higher Education and Medical University of Gdańsk Polish Ministry of Science and Higher Education grant. Project number ST-66. The study was supported by the Medical University of Gdańsk Project No. ST 02-10022 (0000701).
6 · The paper itself

Abstract

Vitiligo is an acquired chronic depigmenting disorder of skin. It is mostly asymptomatic and characterized by amelanotic macules and patches that affects 0.5% to 2% of the world's population. The etiology of vitiligo has not been clearly elucidated and multiple theories have been proposed regarding the causes of the disorder. Among the most prevalent theories, the genetic predisposition, oxidative stress theory, promotion of cellular stress and pathologic influence of lymphocytes T have been highlighted. As a result of increases in in-depth knowledge concerning the pathogenetic processes in vitiligo, we review the most recent information concerning its etiopathogenesis and treatment methods including topical and oral Janus kinase inhibitors, prostaglandins and their analogues, namely afamelanotide, Wnt/β-catenin-signaling agonists and cell-based therapies. Topical ruxolitinib has been registered for vitiligo treatment, whereas other agents as oral ritlecitinib, afamelanotide and latanoprost have been studied in ongoing clinical trials. New highly effective therapeutic strategies may be developed thanks to molecular and genetic studies.

Indexed as

Janus Kinase InhibitorsVitiligoHumansProstaglandinsProtein Kinase InhibitorsSkinJanus Kinase InhibitorsProstaglandinsProtein Kinase InhibitorsJanus kinase inhibitorspathogenesistreatmentvitiligo

Identifiers

PMID37298700
PMCPMC10253679
OpenAlexW4379473481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.