Evidence map›Paper›PMID 37298690›Full record

ArticleInternational journal of molecular sciences2023

Comparison of the Antibacterial Effect of Silver Nanoparticles and a Multifunctional Antimicrobial Peptide on Titanium Surface.

Daniel Moreno, Judit Buxadera-Palomero, Maria-Pau Ginebra, José-María Manero, Helena Martin-Gómez, Carlos Mas-Moruno, Daniel Rodríguez

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Daniel MorenoBiomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Engineering, Universitat Politècnica de Catalunya BarcelonaTech (UPC), Av. Eduard Maristany 16, 08019 Barcelona, Spain.ORCID 0000-0002-9088-3112
Judit Buxadera-PalomeroBiomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Engineering, Universitat Politècnica de Catalunya BarcelonaTech (UPC), Av. Eduard Maristany 16, 08019 Barcelona, Spain.
Maria-Pau GinebraBiomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Engineering, Universitat Politècnica de Catalunya BarcelonaTech (UPC), Av. Eduard Maristany 16, 08019 Barcelona, Spain.ORCID 0000-0002-4700-5621
José-María ManeroBiomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Engineering, Universitat Politècnica de Catalunya BarcelonaTech (UPC), Av. Eduard Maristany 16, 08019 Barcelona, Spain.ORCID 0000-0002-1673-4389
Helena Martin-GómezBiomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Engineering, Universitat Politècnica de Catalunya BarcelonaTech (UPC), Av. Eduard Maristany 16, 08019 Barcelona, Spain.
Carlos Mas-MorunoBiomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Engineering, Universitat Politècnica de Catalunya BarcelonaTech (UPC), Av. Eduard Maristany 16, 08019 Barcelona, Spain.ORCID 0000-0001-8337-0872
Daniel RodríguezBiomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Engineering, Universitat Politècnica de Catalunya BarcelonaTech (UPC), Av. Eduard Maristany 16, 08019 Barcelona, Spain.ORCID 0000-0001-6286-5200
Red de Investigación en Actividades Preventivas y Promoción de la Salud · ESUniversitat Politècnica de Catalunya · ES

Funding

Government of Catalonia ICREA AcademiaGovernment of Catalonia SGR 2017 SGR1165Spanish Ministry of Science and Innovation RTI2018-098075-B-C21Spanish State Research Agency PID2020-114019RB-I00/AEI/10.13039/501100011033Spanish State Research Agency PID2021-125150OB-I00
6 · The paper itself

Abstract

Titanium implantation success may be compromised by Staphylococcus aureus surface colonization and posterior infection. To avoid this issue, different strategies have been investigated to promote an antibacterial character to titanium. In this work, two antibacterial agents (silver nanoparticles and a multifunctional antimicrobial peptide) were used to coat titanium surfaces. The modulation of the nanoparticle (≈32.1 ± 9.4 nm) density on titanium could be optimized, and a sequential functionalization with both agents was achieved through a two-step functionalization method by means of surface silanization. The antibacterial character of the coating agents was assessed individually as well as combined. The results have shown that a reduction in bacteria after 4 h of incubation can be achieved on all the coated surfaces. After 24 h of incubation, however, the individual antimicrobial peptide coating was more effective than the silver nanoparticles or their combination against Staphylococcus aureus. All tested coatings were non-cytotoxic for eukaryotic cells.

Indexed as

Metal NanoparticlesTitaniumAnti-Bacterial AgentsCoated Materials, BiocompatibleSilverStaphylococcus aureusSurface PropertiesAnti-Bacterial AgentsCoated Materials, BiocompatibleSilverTitaniumantimicrobial peptidesilanizationsilver nanoparticlesStaphylococcus aureustitanium functionalization

Identifiers

PMID37298690
PMCPMC10253953
OpenAlexW4379470991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.