Evidence map›Paper›PMID 37298642›Full record

ReviewInternational journal of molecular sciences2023

Next-Generation Sequencing and Triple-Negative Breast Cancer: Insights and Applications.

Domenico Tierno, Gabriele Grassi, Serena Scomersi, Marina Bortul, Daniele Generali, Fabrizio Zanconati, Bruna Scaggiante

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Genomic Alterations in Quadruple-Negative Breast Cancer Tumors.International journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Ossifying fibromyxoid tumor with a novelRespiratory medicine case reports · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Sequencing of high-frequency mutated genes in breast cancer (BRCA) and associated-functions analysis.International journal of clinical and experimental pathology · 2025
    Article
  13. Article
  14. Article
  15. The Genomic and Biologic Landscapes of Breast Cancer and Racial Differences.International journal of molecular sciences · 2024
    Review
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Domenico TiernoDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0003-0858-6192
Gabriele GrassiDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-9704-6651
Serena ScomersiBreast Unit-Azienda Sanitaria Universitaria Integrata Giuliano Isontina ASUGI, University of Trieste, 34149 Trieste, Italy.
Marina BortulDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34149 Trieste, Italy.
Daniele GeneraliDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34149 Trieste, Italy.ORCID 0000-0001-6002-1530
Fabrizio ZanconatiDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34149 Trieste, Italy.
Bruna ScaggianteDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0002-8662-138X
University of Trieste · IT

Funding

Lega Italiana per la Lotta ai Tumori 2022
6 · The paper itself

Abstract

The poor survival of triple-negative breast cancer (TNBC) is due to its aggressive behavior, large heterogeneity, and high risk of recurrence. A comprehensive molecular investigation of this type of breast cancer using high-throughput next-generation sequencing (NGS) methods may help to elucidate its potential progression and discover biomarkers related to patient survival. In this review, the NGS applications in TNBC research are described. Many NGS studies point to

Indexed as

Triple Negative Breast NeoplasmsBiomarkersHigh-Throughput Nucleotide SequencingHumansMutationBiomarkers454-pyrosequencingIlluminaIon Torrentnext-generation sequencingtriple-negative breast cancer

Identifiers

PMID37298642
PMCPMC10253720
OpenAlexW4379229079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.