Evidence map›Paper›PMID 37298506›Full record

Trial reportInternational journal of molecular sciences2023

Kinetic Profile of Urine Metabolites after Acute Intake of a Phenolic Compounds-Rich Juice of Juçara (

Alyne Lizane Cardoso, Luciane de Lira Teixeira, Neuza Mariko Aymoto Hassimotto, Sheyla de Liz Baptista, Cândice Laís Knöner Copetti, Debora Kurrler Rieger, Francilene Gracieli Kunradi Vieira, Gustavo Amadeu Micke, Luciano Vitali, Maria Alice Altenburg de Assis and 4 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Alyne Lizane CardosoGraduate Program in Nutrition, Department of Nutrition, Federal University of Santa Catarina, Florianopolis 88040-900, SC, Brazil.
Luciane de Lira TeixeiraDepartment of Food Science and Experimental Nutrition, University of São Paulo, São Paulo 05508-900, SP, Brazil.
Neuza Mariko Aymoto HassimottoDepartment of Food Science and Experimental Nutrition, University of São Paulo, São Paulo 05508-900, SP, Brazil.ORCID 0000-0002-5576-7693
Sheyla de Liz BaptistaGraduate Program in Nutrition, Department of Nutrition, Federal University of Santa Catarina, Florianopolis 88040-900, SC, Brazil.
Cândice Laís Knöner CopettiGraduate Program in Nutrition, Department of Nutrition, Federal University of Santa Catarina, Florianopolis 88040-900, SC, Brazil.
Debora Kurrler RiegerGraduate Program in Nutrition, Department of Nutrition, Federal University of Santa Catarina, Florianopolis 88040-900, SC, Brazil.
Francilene Gracieli Kunradi VieiraGraduate Program in Nutrition, Department of Nutrition, Federal University of Santa Catarina, Florianopolis 88040-900, SC, Brazil.ORCID 0000-0003-4211-9133
Gustavo Amadeu MickeDepartment of Chemistry, Federal University of Santa Catarina, Florianopolis 88040-900, SC, Brazil.
Luciano VitaliDepartment of Chemistry, Federal University of Santa Catarina, Florianopolis 88040-900, SC, Brazil.
Maria Alice Altenburg de AssisGraduate Program in Nutrition, Department of Nutrition, Federal University of Santa Catarina, Florianopolis 88040-900, SC, Brazil.ORCID 0000-0002-5383-3714
Mayara SchulzDepartment of Food Science and Technology, Federal University of Santa Catarina, Florianopolis 88034-001, SC, Brazil.ORCID 0000-0001-9082-8626
Roseane FettDepartment of Food Science and Technology, Federal University of Santa Catarina, Florianopolis 88034-001, SC, Brazil.
Edson Luiz da SilvaGraduate Program in Nutrition, Department of Clinical Analysis, Federal University of Santa Catarina, Florianopolis 88040-900, SC, Brazil.
Patricia Faria Di PietroGraduate Program in Nutrition, Department of Nutrition, Federal University of Santa Catarina, Florianopolis 88040-900, SC, Brazil.ORCID 0000-0003-1343-5049
Universidade Federal de Santa Catarina · BRUniversidade de São Paulo · BR

Funding

CNPq Scholarship - Brazil 165753/2020-0Coordenação de Aperfeicoamento de Pessoal de Nível Superior Finance Code 001National Council for Scientific and Technological Development MCT/CNPq 14/2012 under Grant [number 483929/2012-3], protocol number 8454-189979648178 and 153453/2012-5São Paulo Research Foundation 2013/07914-8
6 · The paper itself

Abstract

The juçara palm tree produces a small spherical and black-purple fruit similar to açaí. It is rich in phenolic compounds, especially anthocyanins. A clinical trial evaluated the absorption and excretion of the main bioactive compounds in urine and the antioxidant capacity in serum and erythrocytes of 10 healthy subjects after juçara juice intake. Blood samples were collected before (0.0 h) and 0.5 h, 1 h, 2 h, and 4 h after a single dose (400 mL) of juçara juice, while urine was collected at baseline and 0-3 and 3-6 h after juice intake. Seven phenolic acids and conjugated phenolic acids were identified in urine deriving from the degradation of anthocyanins: protocatechuic acid, vanillic acid, vanillic acid glucuronide, hippuric acid, hydroxybenzoic acid, hydroxyphenylacetic acid, and ferulic acid derivative. In addition, kaempferol glucuronide was also found in urine as a metabolite of the parent compound in juçara juice. Juçara juice caused a decrease in the total oxidant status of serum after 0.5 h in comparison to baseline values (

Indexed as

AntioxidantsEuterpeAnthocyaninsErythrocytesFruitGlucuronidesHumansHydroxybenzoatesPhenolsAnthocyaninsAntioxidantsGlucuronidesHydroxybenzoatesphenolic acidPhenolsanthocyaninsantioxidant activityEuterpe edulisphenolic compoundsurine metabolites

Identifiers

PMID37298506
PMCPMC10253860
OpenAlexW4379051536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.