Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
13 authors at 6 institutions in 3 countries.
Lin KangDepartment of Obstetrics and Gynecology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704302, Taiwan.ORCID 0000-0003-2709-5604
Ai-Lun YangInstitute of Sports Sciences, University of Taipei, Taipei 11153, Taiwan.
Chao-Han LaiDepartment of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan 701401, Taiwan.
Tsan-Ju ChenDepartment of Physiology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Sung-Yen LinDepartment of Orthopaedic Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0002-4191-2183
Yan-Hsiung WangOrthopaedic Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0001-8161-7472
Chau-Zen WangDepartment of Physiology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Edward M ConwayCentre for Blood Research, Faculty of Medicine, Life Sciences Institute, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.ORCID 0000-0003-0081-0305
Hua-Lin WuDepartment of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan 701401, Taiwan.
Mei-Ling HoDepartment of Physiology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Je-Ken ChangDepartment of Orthopaedic Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0001-8485-2574
Chung-Hwan ChenDepartment of Orthopaedic Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0001-8941-4792
Tsung-Lin ChengDepartment of Physiology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0001-7080-8652
Kaohsiung Medical University · TWNational Cheng Kung University Hospital · TWNational Sun Yat-sen University · TWNational Cheng Kung University · TWUniversity of British Columbia · CAUniversity of Taipei · TW
Funding
Kaohsiung Medical University KMU-DK(B) 110002Kaohsiung Medical University KMUH-DK(A)110003Kaohsiung Medical University KMU-TC112A02Kaohsiung Municipal Ta-Tung Hospital KMTTH- 111-R002Kaohsiung Municipal Ta-Tung Hospital KMTTH-DK(A)112001Ministry of Science and Technology, Executive Yuan, Taiwan 110-2314-B-006 -037 -MY3Ministry of Science and Technology, Executive Yuan, Taiwan 110-2314-B-037-022-Ministry of Science and Technology, Executive Yuan, Taiwan 110-2314-B-037 -029 -MY3Ministry of Science and Technology, Executive Yuan, Taiwan 111-2314-B-037-055-Ministry of Science and Technology, Executive Yuan, Taiwan 111-2314-B-037-106
6 · The paper itself
Abstract
Osteoarthritis (OA) is a prevalent form of arthritis that affects over 32.5 million adults worldwide, causing significant cartilage damage and disability. Unfortunately, there are currently no effective treatments for OA, highlighting the need for novel therapeutic approaches. Thrombomodulin (TM), a glycoprotein expressed by chondrocytes and other cell types, has an unknown role in OA. Here, we investigated the function of TM in chondrocytes and OA using various methods, including recombinant TM (rTM), transgenic mice lacking the TM lectin-like domain (TM
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Chondrocyte Thrombomodulin Protects against Osteoarthritis. · full record | OpenQuestion